Biphenyl

Biphenyl

SCHEMBL1556544

CC(C)N.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.60
TAAR1 Q96RJ0 4/20 0.50
CYP3A4 P08684 1/20 0.50
HSD17B10 Q99714 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
SLC6A2 P23975 3/20 0.48
SLC6A4 P31645 3/20 0.48
SLC6A3 Q01959 2/20 0.48
MAOA P21397 1/20 0.48
SIGMAR1 Q99720 1/20 0.48
CYP2A6 P11509 1/20 0.48
ADORA2A P29274 1/20 0.48
ADORA1 P30542 1/20 0.48
PTGS2 P35354 1/20 0.46
ADRA2A P08913 1/20 0.46
ADRA2C P18825 1/20 0.46
LMNA P02545 1/20 0.46
HIF1A Q16665 1/20 0.46
KDM4E B2RXH2 1/20 0.46
SLC22A2 O15244 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL27426704 0.97 ALDH1A1 (0.56) ALDH1A1TAAR1CYP3A4HSD17B10TDP1
Biphenyl SCHEMBL28807835 0.88 ADRA2A (0.54) ALDH1A1TAAR1CYP3A4HSD17B10TDP1
Biphenyl SCHEMBL27656690 0.86 ALDH1A1 (0.69) ALDH1A1TAAR1CYP3A4HSD17B10TDP1
Biphenyl SCHEMBL28045686 0.83 MAOA (0.52) ALDH1A1TAAR1SLC6A2SLC6A4SLC6A3
Biphenyl SCHEMBL10980681 0.83 CHRNB2 (0.54) ALDH1A1TAAR1SLC6A2SLC6A4SLC6A3
Biphenyl SCHEMBL27852646 0.83 MAOA (0.52) ALDH1A1TAAR1SLC6A2SLC6A4SLC6A3
Biphenyl SCHEMBL27519887 0.83 ALDH1A1 (0.64) ALDH1A1TAAR1CYP3A4HSD17B10TDP1
Isopropylamine SCHEMBL5993622 0.82 CYP3A4 (0.44) ALDH1A1TAAR1CYP3A4HSD17B10TDP1
Biphenyl SCHEMBL1557083 0.82 ALDH1A1 (0.75) ALDH1A1TAAR1CYP3A4HSD17B10TDP1
Biphenyl SCHEMBL27927789 0.82 ALDH1A1 (0.75) ALDH1A1TAAR1CYP3A4HSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105503946-A Method for making hydroxymethylphosphonate, polyurethane foam-forming compositions, polyurethane foam and articles made therefrom ICL-IP America Inc 2016-04-20 CN claimed
CN-102256987-B Hydroxymethylphosphonate, polyurethane foam-forming compositions, polyurethane foams, and methods of making articles made therefrom ICL-IP AMERICA INC. (US) 2016-01-13 CN claimed
EP-1971664-B1 EMITTING MATERIALS AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME LG CHEMICAL LTD (KR) 2015-09-09 EP claimed
CN-102256987-A Hydroxymethylphosphonate, polyurethane foam-forming compositions, polyurethane foams, and methods of making articles made therefrom ICL IP AMERICAN CORP 2011-11-23 CN claimed
US-7919196-B2 Emitting materials and organic light emitting device using the same LG CHEM, LTD. (KR) 2011-04-05 US claimed
US-20090021149-A1 Emitting Materials and Organic Light Emitting Device Using the Same LG CHEM. LTD. (KR) 2009-01-22 US claimed
EP-1971664-A1 EMITTING MATERIALS AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME LG Chem, Ltd. (KR) 2008-09-24 EP claimed
WO-2007081179-A1 EMITTING MATERIALS AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME LG CHEM. LTD. (KR) 2007-07-19 WO claimed
CN-105503946-A Method for making hydroxymethylphosphonate, polyurethane foam-forming compositions, polyurethane foam and articles made therefrom ICL-IP America Inc 2016-04-20 CN disclosed
CN-102256987-B Hydroxymethylphosphonate, polyurethane foam-forming compositions, polyurethane foams, and methods of making articles made therefrom ICL-IP AMERICA INC. (US) 2016-01-13 CN disclosed
EP-1971664-B1 EMITTING MATERIALS AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME LG CHEMICAL LTD (KR) 2015-09-09 EP disclosed
CN-102256987-A Hydroxymethylphosphonate, polyurethane foam-forming compositions, polyurethane foams, and methods of making articles made therefrom ICL IP AMERICAN CORP 2011-11-23 CN disclosed
US-7919196-B2 Emitting materials and organic light emitting device using the same LG CHEM, LTD. (KR) 2011-04-05 US disclosed
US-20090021149-A1 Emitting Materials and Organic Light Emitting Device Using the Same LG CHEM. LTD. (KR) 2009-01-22 US disclosed
EP-1971664-A1 EMITTING MATERIALS AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME LG Chem, Ltd. (KR) 2008-09-24 EP disclosed
WO-2007081179-A1 EMITTING MATERIALS AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME LG CHEM. LTD. (KR) 2007-07-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090021149-A1 Emitting Materials and Organic Light Emitting Device Using the Same CRY1, CRY2, PER2 ALDH1A1 112/4885TAAR1 2262/4885CYP3A4 601/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.