SCHEMBL28999983

SCHEMBL28999983

COC(=O)C1(C(=O)OC)CC1/C=C/[N+](=O)[O-]

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
CYP3A4 P08684 1/20 0.31
TSHR P16473 1/20 0.31
CYP2C19 P33261 1/20 0.31
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28999965 0.83 SMN1; SMN2 (0.30)
SCHEMBL28999995 0.83 FBP1 (0.33) CYP3A4CYP2C19MAPT
SCHEMBL28999977 0.83
SCHEMBL28999969 0.77 EPHX2 (0.31)
SCHEMBL11599824 0.74 CYP4F2 (0.31) MAPT
SCHEMBL11511413 0.72 MAPT (0.33) MAPT
SCHEMBL28999973 0.72 CTSL (0.41) KMT2A
SCHEMBL12530121 0.71 MAPT (0.33) CYP3A4TSHRCYP2C19MAPT
SCHEMBL812061 0.71 MAPT (0.33) CYP3A4TSHRCYP2C19MAPT
SCHEMBL28999992 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113121357-B 2-nitrovinyl cyclopropane compound and synthesis method thereof 上海大学 2023-05-16 CN disclosed
CN-113121357-A 2-nitrovinyl cyclopropane compound and synthetic method thereof 上海大学 2021-07-16 CN disclosed