SCHEMBL28999973

SCHEMBL28999973

O=C(OCc1ccccc1)C1(C(=O)OCc2ccccc2)CC1/C=C/[N+](=O)[O-]

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CTSL P07711 8/20 0.41
CTSB P07858 8/20 0.41
DDB1 Q16531 1/20 0.39
CRBN Q96SW2 1/20 0.39
TLR4 O00206 1/20 0.38
TLR2 O60603 1/20 0.38
MAOA P21397 1/20 0.38
MAOB P27338 1/20 0.38
ALDH1A1 P00352 3/20 0.38
CYP17A1 P05093 2/20 0.38
CYP19A1 P11511 2/20 0.38
HCAR2 Q8TDS4 1/20 0.38
TDP1 Q9NUW8 2/20 0.37
MAPK1 P28482 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
SLC6A2 P23975 1/20 0.37
SLC6A3 Q01959 1/20 0.37
KMT2A Q03164 1/20 0.37
PDE1C Q14123 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28999976 0.79 DDB1 (0.44) DDB1CRBNALDH1A1CYP17A1CYP19A1
SCHEMBL28999995 0.77 FBP1 (0.33) ALDH1A1MAPK1
SCHEMBL28999969 0.75 EPHX2 (0.31)
SCHEMBL28999983 0.72 MEN1 (0.32) KMT2A
SCHEMBL32674103 0.72 ALDH1A1 (0.53) DDB1CRBNALDH1A1CYP17A1CYP19A1
SCHEMBL28999972 0.72 FBP1 (0.39) TLR4TLR2MAOAMAOBALDH1A1
SCHEMBL7561982 0.71 HCAR2 (0.63) CTSLCTSBTLR4TLR2MAOA
SCHEMBL25213325 0.70 ALDH1A1 (0.46) DDB1CRBNMAOAMAOBALDH1A1
SCHEMBL25317306 0.70 ALDH1A1 (0.50) DDB1CRBNALDH1A1CYP17A1CYP19A1
SCHEMBL32674206 0.70 ALDH1A1 (0.50) DDB1CRBNALDH1A1CYP17A1CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113121357-B 2-nitrovinyl cyclopropane compound and synthesis method thereof 上海大学 2023-05-16 CN disclosed
CN-113121357-A 2-nitrovinyl cyclopropane compound and synthetic method thereof 上海大学 2021-07-16 CN disclosed