Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.34 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.34 |
| ▸ | C1S | P09871 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28366435 | 0.75 | GABRA5 (0.36) | AOC3ALDH1A1KMT2AHPGD | |
| SCHEMBL4753884 | 0.71 | HTR2B (0.39) | ALDH1A1MAPT | |
| SCHEMBL23933151 | 0.71 | AOC3 (0.50) | AOC3ALDH1A1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL28803151 | 0.69 | AOC3 (0.33) | AOC3 | |
| SCHEMBL24622258 | 0.68 | AOC3 (0.47) | AOC3ALDH1A1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL23933145 | 0.68 | KMT2A (0.35) | ALDH1A1RAB9AMAPTSMN1; SMN2KMT2A | |
| SCHEMBL28366125 | 0.67 | KDM4E (0.31) | ALDH1A1 | |
| SCHEMBL10081937 | 0.65 | KMT2A (0.58) | ALDH1A1MAPTSMN1; SMN2KMT2APARP10 | |
| SCHEMBL15881332 | 0.65 | POLB (0.43) | ALDH1A1RAB9AMAPTSMN1; SMN2NPC1 | |
| SCHEMBL22322104 | 0.65 | ALDH5A1 (0.45) | ALDH1A1RAB9AMAPTSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117015381-A | Novel steroid payloads, steroid linkers, ADCs containing the same and uses thereof | 伊穆奈克斯特股份有限公司 | 2023-11-07 | — | — | CN | disclosed |
| CN-116096413-A | Anti-human VISTA antibodies and uses thereof | 伊穆奈克斯特股份有限公司 | 2023-05-09 | — | — | CN | disclosed |