Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.76 |
| ▸ | F10 | P00742 | 1/20 | 0.76 |
| ▸ | PLG | P00747 | 1/20 | 0.76 |
| ▸ | PLAU | P00749 | 1/20 | 0.76 |
| ▸ | PLAT | P00750 | 1/20 | 0.76 |
| ▸ | HPN | P05981 | 1/20 | 0.76 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.76 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.76 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.76 |
| ▸ | CHEK2 | O96017 | 18/20 | 0.69 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.60 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4315225 | 0.86 | F2 (1.00) | F2F10PLGPLAUPLAT | |
| SCHEMBL20088842 | 0.84 | HDAC6 (0.76) | F2F10PLGPLAUPLAT | |
| SCHEMBL7972795 | 0.84 | F10 (0.61) | F2F10PLGPLAUPLAT | |
| SCHEMBL10140088 | 0.82 | CHEK2 (0.54) | F2F10PLGPLAUPLAT | |
| SCHEMBL31612174 | 0.82 | ADORA2A (0.64) | F2F10PLGPLAUPLAT | |
| SCHEMBL4507302 | 0.80 | CHEK2 (0.59) | F2F10PLGPLAUPLAT | |
| SCHEMBL28668397 | 0.80 | F2 (0.67) | F2F10PLGPLAUPLAT | |
| SCHEMBL20982670 | 0.80 | CHEK2 (0.86) | CHEK2PKN1PKN2 | |
| SCHEMBL5679988 | 0.77 | CHEK2 (1.00) | CHEK2 | |
| SCHEMBL30832867 | 0.77 | CHEK2 (0.82) | F2F10CHEK2PKN1PKN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115960930-A | Use of PLAU and PSMA4 targets in prevention and treatment of aortic aneurysms | 华中科技大学同济医学院附属同济医院 | 2023-04-14 | — | — | CN | disclosed |