Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 6/20 | 0.82 |
| ▸ | F2 | P00734 | 1/20 | 0.77 |
| ▸ | F10 | P00742 | 1/20 | 0.77 |
| ▸ | F7 | P08709 | 1/20 | 0.77 |
| ▸ | CBFB | Q13951 | 6/20 | 0.65 |
| ▸ | METAP2 | P50579 | 5/20 | 0.65 |
| ▸ | NPC1 | O15118 | 5/20 | 0.65 |
| ▸ | RAB9A | P51151 | 5/20 | 0.65 |
| ▸ | HPGD | P15428 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.65 |
| ▸ | PKM | P14618 | 3/20 | 0.65 |
| ▸ | TP53 | P04637 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.62 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6686459 | 0.90 | CHEK2 (1.00) | CHEK2F2F10F7PKN1 | |
| SCHEMBL29517866 | 0.90 | CHEK2 (0.67) | CHEK2F2F10F7CBFB | |
| SCHEMBL179156 | 0.90 | CHEK2 (0.67) | CHEK2F2F10F7CBFB | |
| SCHEMBL19970726 | 0.88 | F2 (0.70) | CHEK2F2F10F7CBFB | |
| SCHEMBL11035024 | 0.87 | METAP1 (0.70) | CHEK2F2F10F7CBFB | |
| SCHEMBL7371342 | 0.87 | F2 (1.00) | CHEK2F2F10F7CBFB | |
| SCHEMBL19982677 | 0.84 | F2 (0.65) | CHEK2F2F10F7CBFB | |
| SCHEMBL32660766 | 0.84 | F2 (0.65) | CHEK2F2F10F7CBFB | |
| SCHEMBL7368937 | 0.81 | F2 (0.67) | CHEK2F2F10F7CBFB | |
| SCHEMBL3921720 | 0.80 | CHEK2 (0.83) | CHEK2HPGDKDM4EMAPTPKN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111315735-B | Dihydrobenzimidazolone | C4医药公司 | 2024-03-08 | — | — | CN | disclosed |