Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 10/20 | 0.54 |
| ▸ | DGAT1 | O75907 | 7/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.51 |
| ▸ | SOAT1 | P35610 | 3/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31027889 | 0.84 | HDAC6 (0.64) | NPBWR1DGAT1KCNH2SOAT1HDAC6 | |
| SCHEMBL21705325 | 0.84 | HDAC6 (0.64) | NPBWR1DGAT1KCNH2SOAT1HDAC6 | |
| SCHEMBL15245227 | 0.83 | HDAC6 (0.62) | NPBWR1DGAT1KCNH2SOAT1HDAC6 | |
| SCHEMBL15245140 | 0.82 | DGAT1 (0.67) | NPBWR1DGAT1KCNH2SOAT1TRPV1 | |
| SCHEMBL24074323 | 0.81 | HDAC6 (0.60) | NPBWR1DGAT1KCNH2SOAT1HDAC6 | |
| SCHEMBL20661102 | 0.81 | KDM4E (0.59) | NPBWR1DGAT1KCNH2 | |
| SCHEMBL20661007 | 0.80 | PARP1 (0.53) | NPBWR1DGAT1KCNH2 | |
| SCHEMBL15245237 | 0.80 | KIF11 (0.59) | NPBWR1DGAT1KCNH2SOAT1HDAC6 | |
| SCHEMBL19994514 | 0.79 | NPBWR1 (0.50) | NPBWR1DGAT1KCNH2SOAT1 | |
| SCHEMBL30343725 | 0.79 | NPBWR1 (0.50) | NPBWR1DGAT1KCNH2SOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110234640-B | Benzimidazole derivatives as anticancer agents | 利昂贝拉尔中心 | 2023-04-07 | — | — | CN | disclosed |