Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.52 |
| ▸ | AKT2 | P31751 | 1/20 | 0.52 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.45 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.45 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.44 |
| ▸ | TNF | P01375 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.43 |
| ▸ | ILK | Q13418 | 1/20 | 0.42 |
| ▸ | CLK2 | P49760 | 3/20 | 0.42 |
| ▸ | HIPK1 | Q86Z02 | 3/20 | 0.42 |
| ▸ | HIPK2 | Q9H2X6 | 3/20 | 0.42 |
| ▸ | HIPK3 | Q9H422 | 3/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.42 |
| ▸ | DYRK2 | Q92630 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29276383 | 0.84 | AKT1 (0.47) | AKT1AKT2PDK2AURKAAURKB | |
| SCHEMBL28546134 | 0.77 | AKT1 (0.43) | AKT1AKT2PDK2AURKAAURKB | |
| SCHEMBL30823568 | 0.76 | AKT2 (0.59) | AKT1AKT2PDK2AURKAAURKB | |
| SCHEMBL28552255 | 0.76 | AKT2 (0.72) | AKT1AKT2PDK2AURKAAURKB | |
| SCHEMBL30823569 | 0.76 | AKT2 (0.59) | AKT1AKT2PDK2AURKAAURKB | |
| SCHEMBL10901163 | 0.76 | MCL1 (0.50) | MCL1TNFKDM4EGSK3BCA12 | |
| SCHEMBL15507900 | 0.76 | AURKA (0.41) | AKT1AKT2PDK2AURKAAURKB | |
| SCHEMBL22861262 | 0.75 | MCL1 (0.52) | AKT1AKT2MCL1ROCK2ROCK1 | |
| SCHEMBL30144924 | 0.75 | METAP2 (0.67) | AKT1AKT2AURKAAURKBINCENP | |
| SCHEMBL38660231 | 0.75 | PRKCZ (0.59) | AKT1AKT2AURKBROCK2CLK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116139936-A | Carbonic anhydrase artificial enzyme and preparation method and application thereof | 四川大学 | 2023-05-23 | — | — | CN | claimed |
| CN-116139936-B | Carbonic anhydrase artificial enzyme and preparation method and application thereof | 四川大学 | 2023-07-04 | — | — | CN | disclosed |
| CN-116139936-B | Carbonic anhydrase artificial enzyme and preparation method and application thereof | 四川大学 | 2023-07-04 | — | — | CN | disclosed |
| CN-116139936-A | Carbonic anhydrase artificial enzyme and preparation method and application thereof | 四川大学 | 2023-05-23 | — | — | CN | disclosed |
| CN-116139936-A | Carbonic anhydrase artificial enzyme and preparation method and application thereof | 四川大学 | 2023-05-23 | — | — | CN | disclosed |