Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKBIA | P25963 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.53 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.51 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.50 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.50 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29002561 | 0.80 | ALDH1A1 (0.55) | ALDH1A1KDM4ELMNASMN1; SMN2MAPT | |
| SCHEMBL4822277 | 0.76 | SMN1; SMN2 (0.67) | NFKBIALMNASMN1; SMN2MAPTFFAR4 | |
| SCHEMBL25351338 | 0.75 | FFAR4 (0.55) | ALDH1A1KDM4ELMNASMN1; SMN2HPGD | |
| SCHEMBL7824834 | 0.75 | ALDH1A1 (0.78) | ALDH1A1KDM4ELMNASMN1; SMN2MAPT | |
| SCHEMBL25351854 | 0.75 | PGR (0.54) | ALDH1A1KDM4ELMNASMN1; SMN2HPGD | |
| SCHEMBL28007445 | 0.75 | KDM4E (0.64) | NFKBIAALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL7833927 | 0.74 | HTR6 (0.72) | ALDH1A1KDM4ELMNASMN1; SMN2MAPT | |
| SCHEMBL1055106 | 0.72 | KDM4E (0.72) | ALDH1A1KDM4ELMNASMN1; SMN2MAPT | |
| SCHEMBL26927349 | 0.71 | CCR4 (0.44) | ALDH1A1KDM4EMAPTHPGDTSHR | |
| SCHEMBL28728869 | 0.71 | FFAR4 (0.63) | NFKBIAALDH1A1KDM4ELMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116143708-A | Polysubstituted benzazepine heteroaryl derivative and application thereof | 四川汇宇制药股份有限公司 | 2023-05-23 | — | — | CN | disclosed |