Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 2/20 | 0.33 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.33 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | CETP | P11597 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | SMO | Q99835 | 1/20 | 0.30 |
| ▸ | CFD | P00746 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29003135 | 1.00 | JAK3 (0.33) | JAK3P2RY12CXCR3MAPTALDH1A1 | |
| SCHEMBL29003138 | 0.86 | GPR119 (0.41) | — | |
| SCHEMBL30456370 | 0.86 | GPR119 (0.41) | — | |
| SCHEMBL29003136 | 0.86 | GPR119 (0.41) | — | |
| SCHEMBL29003133 | 0.85 | SLC6A7 (0.40) | ALDH1A1MEN1KMT2ASMO | |
| SCHEMBL29003128 | 0.85 | SLC6A7 (0.40) | ALDH1A1MEN1KMT2ASMO | |
| SCHEMBL27233727 | 0.74 | MDM2 (0.41) | CXCR3MAPTALDH1A1CETPMEN1 | |
| SCHEMBL27233731 | 0.74 | MDM2 (0.41) | CXCR3MAPTALDH1A1CETPMEN1 | |
| SCHEMBL10372774 | 0.74 | SLC6A7 (0.46) | P2RY12ALDH1A1 | |
| SCHEMBL27233813 | 0.74 | MDM2 (0.41) | CXCR3MAPTALDH1A1CETPMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116157122-A | Imidazo [1,2-a ] pyridine compounds and their use in therapy | 帝国理工学院创新有限公司 | 2023-05-23 | — | — | CN | disclosed |