Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 13/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27126798 | 0.86 | LMNA (0.48) | NOTUMTDP1 | |
| SCHEMBL29003132 | 0.83 | CHRM4 (0.43) | CHRM4GRM4 | |
| SCHEMBL29765410 | 0.77 | HTT (0.40) | — | |
| SCHEMBL18952560 | 0.73 | CHRNB2 (0.36) | CHRM4 | |
| SCHEMBL18952562 | 0.73 | CHRNB2 (0.36) | CHRM4 | |
| SCHEMBL21726801 | 0.73 | CHRNB2 (0.36) | CHRM4 | |
| SCHEMBL25689702 | 0.71 | IP6K1 (0.40) | POLB | |
| SCHEMBL21434033 | 0.71 | P4HTM (0.46) | NOTUMPOLBTDP1L3MBTL1 | |
| SCHEMBL16635304 | 0.71 | CHRNB2 (0.38) | — | |
| SCHEMBL21434132 | 0.70 | SMO (0.45) | CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116157122-A | Imidazo [1,2-a ] pyridine compounds and their use in therapy | 帝国理工学院创新有限公司 | 2023-05-23 | — | — | CN | disclosed |
| WO-2022058745-A9 | IMIDAZO[1,2-A]PYRIDINE COMPOUNDS AND THEIR USE IN THERAPY | IMPERIAL COLLEGE INNOVATIONS LIMITED (GB) | 2022-05-27 | — | — | WO | disclosed |