Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | HMGCR | P04035 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 2/20 | 0.31 |
| ▸ | RXRB | P28702 | 2/20 | 0.31 |
| ▸ | RXRG | P48443 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6573426 | 0.76 | TP53 (0.46) | GABRA1GABRB2MAPTTP53CYP3A4 | |
| SCHEMBL7735185 | 0.76 | GABRA1 (0.42) | GABRA1GABRB2HMGCRMAPTTP53 | |
| SCHEMBL6573320 | 0.76 | TP53 (0.46) | GABRA1GABRB2MAPTTP53CYP3A4 | |
| SCHEMBL29029007 | 0.76 | CYP1A2 (0.55) | MAPTMAPK1SMN1; SMN2POLBCYP1A2 | |
| SCHEMBL6573201 | 0.76 | TP53 (0.46) | GABRA1GABRB2MAPTTP53CYP3A4 | |
| SCHEMBL16900183 | 0.76 | CYP1A2 (0.55) | MAPTMAPK1SMN1; SMN2POLBCYP1A2 | |
| SCHEMBL28946049 | 0.74 | GABRA1 (0.50) | GABRA1GABRB2HMGCRMAPTTP53 | |
| SCHEMBL12269360 | 0.73 | PTGS1 (0.43) | SMN1; SMN2POLBCYP1A2GABBR2GABBR1 | |
| SCHEMBL2427389 | 0.73 | GABRA1 (0.39) | GABRA1GABRB2HMGCRMAPTTP53 | |
| SCHEMBL6575448 | 0.73 | APP (0.43) | GABRA1GABRB2HMGCRMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114957016-B | Synthesis method of o-diamine compound | 江南大学 | 2023-07-04 | — | — | CN | disclosed |
| CN-114957016-A | Synthesis method of o-diamine compound | 江南大学 | 2022-08-30 | — | — | CN | disclosed |