Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 3/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | HMGCR | P04035 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.32 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.32 |
| ▸ | TUBB | P07437 | 1/20 | 0.32 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13913127 | 1.00 | APP (0.43) | APPGABRA1GABRB2HMGCRMAPT | |
| SCHEMBL6573426 | 0.82 | TP53 (0.46) | APPGABRA1GABRB2MAPTTP53 | |
| SCHEMBL6573320 | 0.82 | TP53 (0.46) | APPGABRA1GABRB2MAPTTP53 | |
| SCHEMBL6573201 | 0.82 | TP53 (0.46) | APPGABRA1GABRB2MAPTTP53 | |
| SCHEMBL3264978 | 0.78 | GABRA1 (0.39) | GABRA1GABRB2HMGCRMAPTTP53 | |
| SCHEMBL2032568 | 0.78 | GABRA1 (0.39) | GABRA1GABRB2HMGCRMAPTTP53 | |
| SCHEMBL3201259 | 0.78 | GABRA1 (0.39) | GABRA1GABRB2HMGCRMAPTTP53 | |
| SCHEMBL6571930 | 0.78 | GABRA1 (0.39) | GABRA1GABRB2HMGCRMAPTTP53 | |
| SCHEMBL2427389 | 0.78 | GABRA1 (0.39) | GABRA1GABRB2HMGCRMAPTTP53 | |
| SCHEMBL190968 | 0.78 | GABRA1 (0.52) | GABRA1GABRB2MAPTCYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1027398-B1 | LIGHT-EMITTING DENDRIMERS AND DEVICES | ISIS INNOVATION (GB) | 2004-06-09 | — | — | EP | disclosed |
| US-6720093-B2 | DEVICE INCORPORATING AS, OR IN, ITS LIGHT-EMITTING ELEMENT LUMINESCENT COMPOUND INCLUDING CONJUGATED DENDRITIC MOLECULAR STRUCTURE COMPRISING GROUPS SELECTED FROM ARYL AND HETEROARYL GROUPS AND ALKENYL GROUPS CONNECTED TO EACH OTHER | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 2004-04-13 | — | — | US | disclosed |
| US-20030165716-A1 | Dendrimers according to present invention which can be used for incorporation into light emitting devices have core and/or branches comprising electroluminescent or charge-transporting chromophores (conjugated units) | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 2003-09-04 | — | — | US | disclosed |
| US-6558818-B1 | Light-emitting dendrimers and devices | ISIS INNOVATION LTD. (GB) | 2003-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030165716-A1 | Dendrimers according to present invention which can be used for incorporation into light emitting devices have core and/or branches comprising electroluminescent or charge-transporting chromophores (conjugated units) | CLTB, CLTA, CLTC | APP 1226/4885GABRA1 1200/4885GABRB2 763/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.