Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 5/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.39 |
| ▸ | DGKA | P23743 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29004650 | 1.00 | FAAH (0.47) | FAAHCNR1CNR2CES2LMNA | |
| SCHEMBL29004667 | 1.00 | FAAH (0.47) | FAAHCNR1CNR2CES2LMNA | |
| SCHEMBL13437114 | 0.84 | TERT (0.47) | FAAHCNR2LMNAFFAR1FFAR4 | |
| SCHEMBL9136425 | 0.81 | DNM1 (0.48) | FAAHCNR1CNR2LMNAEPHX2 | |
| SCHEMBL10350856 | 0.81 | DNM1 (0.48) | FAAHCNR1CNR2LMNAEPHX2 | |
| SCHEMBL11673316 | 0.81 | DNM1 (0.48) | FAAHCNR1CNR2LMNAEPHX2 | |
| SCHEMBL3039218 | 0.81 | DNM1 (0.48) | FAAHCNR1CNR2LMNAEPHX2 | |
| SCHEMBL4022359 | 0.81 | DNM1 (0.48) | FAAHCNR1CNR2LMNAEPHX2 | |
| SCHEMBL4018867 | 0.81 | DNM1 (0.48) | FAAHCNR1CNR2LMNAEPHX2 | |
| SCHEMBL690816 | 0.81 | DNM1 (0.48) | FAAHCNR1CNR2LMNAEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116171272-A | Novel VDAC1 inhibitors | 阿巴尔塞奥制药公司 | 2023-05-26 | — | — | CN | disclosed |