Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNK | O75909 | 9/20 | 0.44 |
| ▸ | CDK12 | Q9NYV4 | 9/20 | 0.44 |
| ▸ | CCNT1 | O60563 | 7/20 | 0.44 |
| ▸ | CDK9 | P50750 | 7/20 | 0.44 |
| ▸ | CDK7 | P50613 | 7/20 | 0.44 |
| ▸ | CCNH | P51946 | 7/20 | 0.44 |
| ▸ | MNAT1 | P51948 | 7/20 | 0.44 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.43 |
| ▸ | CCNE1 | P24864 | 5/20 | 0.41 |
| ▸ | CDK2 | P24941 | 5/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 6/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 2/20 | 0.39 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL29005450 | 0.91 | HRH4 (0.40) | CHEK1AURKARPS6KB1 | |
| Trifluoroacetic Acid SCHEMBL29005533 | 0.84 | CHEK1 (0.39) | CCNKCDK12CCNT1CDK9CDK7 | |
| Trifluoroacetic Acid SCHEMBL29005531 | 0.83 | HRH4 (0.41) | CCNKCDK12CCNT1CDK9CDK7 | |
| Trifluoroacetic Acid SCHEMBL29005619 | 0.79 | MAOA (0.35) | CHEK1 | |
| Trifluoroacetic Acid SCHEMBL29363458 | 0.79 | CCNT1 (0.59) | CCNKCDK12CCNT1CDK9CDK7 | |
| Trifluoroacetic Acid SCHEMBL29005633 | 0.75 | HRH4 (0.40) | CDK7CCNHMNAT1IRAK4CCNE1 | |
| Trifluoroacetic Acid SCHEMBL29005569 | 0.73 | PARP1 (0.34) | CHEK1KCNH2 | |
| SCHEMBL25027665 | 0.69 | CCNT1 (0.60) | CCNKCDK12CCNT1CDK9CDK7 | |
| Trifluoroacetic Acid SCHEMBL29363835 | 0.69 | CCNT1 (0.46) | CCNKCDK12CCNT1CDK9CDK7 | |
| Trifluoroacetic Acid SCHEMBL31006787 | 0.68 | IRAK4 (0.49) | CCNKCDK12CCNT1CDK9CDK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115996926-A | Indole compounds as androgen receptor modulators | 尼多生物科学有限公司 | 2023-04-21 | — | — | CN | disclosed |