Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.39 |
| ▸ | CCNK | O75909 | 3/20 | 0.36 |
| ▸ | CDK12 | Q9NYV4 | 3/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.36 |
| ▸ | CDK7 | P50613 | 2/20 | 0.36 |
| ▸ | CDK9 | P50750 | 2/20 | 0.36 |
| ▸ | CCNH | P51946 | 2/20 | 0.36 |
| ▸ | MNAT1 | P51948 | 2/20 | 0.36 |
| ▸ | FLT3 | P36888 | 2/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 5/20 | 0.34 |
| ▸ | CHEK2 | O96017 | 3/20 | 0.34 |
| ▸ | BRD4 | O60885 | 2/20 | 0.34 |
| ▸ | ATAD2 | Q6PL18 | 2/20 | 0.34 |
| ▸ | JUN | P05412 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL29005459 | 0.83 | CCNK (0.44) | IRAK4CCNKCDK12CCNT1CDK7 | |
| Trifluoroacetic Acid SCHEMBL29005450 | 0.82 | HRH4 (0.40) | HRH4HRH3CHEK1BRD4ATAD2 | |
| Trifluoroacetic Acid SCHEMBL29364340 | 0.79 | CCNT1 (0.51) | HRH4HRH3IRAK4CCNKCDK12 | |
| Trifluoroacetic Acid SCHEMBL29005619 | 0.78 | MAOA (0.35) | HRH4HRH3CHEK1 | |
| Trifluoroacetic Acid SCHEMBL29005635 | 0.78 | TERT (0.41) | CDK2 | |
| Trifluoroacetic Acid SCHEMBL29005533 | 0.77 | CHEK1 (0.39) | IRAK4CCNKCDK12CCNT1CDK7 | |
| Trifluoroacetic Acid SCHEMBL29005569 | 0.74 | PARP1 (0.34) | FLT3CHEK1 | |
| SCHEMBL25028765 | 0.68 | CCNT1 (0.52) | CCNKCDK12CCNT1CDK7CDK9 | |
| Trifluoroacetic Acid SCHEMBL29782734 | 0.68 | IRAK4 (0.40) | HRH4HRH3IRAK4FLT3BRD4 | |
| SCHEMBL30478179 | 0.67 | CHEK1 (0.43) | CCNKCDK12CCNT1CDK7CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115996926-A | Indole compounds as androgen receptor modulators | 尼多生物科学有限公司 | 2023-04-21 | — | — | CN | disclosed |