Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.46 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30285809 | 1.00 | KMT2A (0.58) | KMT2ATSHRNPSR1SMN1; SMN2NPC1 | |
| SCHEMBL30285857 | 0.91 | SMN1; SMN2 (0.60) | KMT2ATSHRNPSR1SMN1; SMN2NPC1 | |
| SCHEMBL29005545 | 0.91 | SMN1; SMN2 (0.60) | KMT2ATSHRNPSR1SMN1; SMN2NPC1 | |
| SCHEMBL26186454 | 0.87 | KMT2A (0.57) | KMT2ATSHRNPSR1SMN1; SMN2NPC1 | |
| SCHEMBL30285630 | 0.87 | KMT2A (0.57) | KMT2ATSHRNPSR1SMN1; SMN2NPC1 | |
| SCHEMBL29029246 | 0.84 | SMN1; SMN2 (0.49) | KMT2ASMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL30403470 | 0.84 | SMN1; SMN2 (0.49) | KMT2ASMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL30285766 | 0.83 | SMN1; SMN2 (0.64) | KMT2ATSHRNPSR1SMN1; SMN2NPC1 | |
| SCHEMBL26186443 | 0.83 | SMN1; SMN2 (0.64) | KMT2ATSHRNPSR1SMN1; SMN2NPC1 | |
| SCHEMBL30285408 | 0.81 | SMN1; SMN2 (0.56) | KMT2ATSHRNPSR1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115996911-A | Substituted N-phenylacetamides having P2X4 receptor antagonistic activity | 拜耳公司 | 2023-04-21 | — | — | CN | disclosed |