Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
| ▸ | KCNJ5 | P48544 | 3/20 | 0.46 |
| ▸ | KCNJ3 | P48549 | 3/20 | 0.46 |
| ▸ | ACKR3 | P25106 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.42 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30403470 | 1.00 | SMN1; SMN2 (0.49) | SMN1; SMN2MEN1KMT2AROCK2KCNJ5 | |
| SCHEMBL29029217 | 0.90 | ROCK2 (0.48) | SMN1; SMN2MEN1KMT2AROCK2KCNJ5 | |
| SCHEMBL30403682 | 0.90 | ROCK2 (0.48) | SMN1; SMN2MEN1KMT2AROCK2KCNJ5 | |
| SCHEMBL26186457 | 0.86 | SMN1; SMN2 (0.46) | SMN1; SMN2MEN1KMT2AROCK2KCNJ5 | |
| SCHEMBL30285736 | 0.86 | SMN1; SMN2 (0.46) | SMN1; SMN2MEN1KMT2AROCK2KCNJ5 | |
| SCHEMBL30285809 | 0.84 | KMT2A (0.58) | SMN1; SMN2MEN1KMT2AMAPTLMNA | |
| SCHEMBL29005502 | 0.84 | KMT2A (0.58) | SMN1; SMN2MEN1KMT2AMAPTLMNA | |
| SCHEMBL30285583 | 0.83 | ROCK2 (0.49) | ROCK2ACKR3ALDH1A1ANO1RECQL | |
| SCHEMBL26186442 | 0.83 | ROCK2 (0.49) | ROCK2ACKR3ALDH1A1ANO1RECQL | |
| SCHEMBL30285756 | 0.81 | ROCK2 (0.44) | SMN1; SMN2MEN1KMT2AROCK2KCNJ5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115989218-A | Use of N-phenylacetamides having P2X4 receptor antagonistic activity for the treatment of certain eye diseases | 拜耳公司 | 2023-04-18 | — | — | CN | disclosed |