Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30285857 | 1.00 | SMN1; SMN2 (0.60) | SMN1; SMN2KMT2ATSHRNPSR1LMNA | |
| SCHEMBL29005502 | 0.91 | KMT2A (0.58) | SMN1; SMN2KMT2ATSHRNPSR1LMNA | |
| SCHEMBL30285809 | 0.91 | KMT2A (0.58) | SMN1; SMN2KMT2ATSHRNPSR1LMNA | |
| SCHEMBL24173309 | 0.86 | SMN1; SMN2 (0.56) | SMN1; SMN2KMT2ATSHRNPSR1LMNA | |
| SCHEMBL30285800 | 0.86 | SMN1; SMN2 (0.56) | SMN1; SMN2KMT2ATSHRNPSR1LMNA | |
| SCHEMBL30285766 | 0.84 | SMN1; SMN2 (0.64) | SMN1; SMN2KMT2ATSHRNPSR1LMNA | |
| SCHEMBL26186443 | 0.84 | SMN1; SMN2 (0.64) | SMN1; SMN2KMT2ATSHRNPSR1LMNA | |
| SCHEMBL30403682 | 0.81 | ROCK2 (0.48) | SMN1; SMN2KMT2APOLBALDH1A1MAPT | |
| SCHEMBL29029217 | 0.81 | ROCK2 (0.48) | SMN1; SMN2KMT2APOLBALDH1A1MAPT | |
| SCHEMBL30285785 | 0.81 | SMN1; SMN2 (0.50) | SMN1; SMN2KMT2ATSHRNPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115996911-A | Substituted N-phenylacetamides having P2X4 receptor antagonistic activity | 拜耳公司 | 2023-04-21 | — | — | CN | disclosed |