Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 6/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.41 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.41 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.40 |
| ▸ | GALR3 | O60755 | 1/20 | 0.40 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29029217 | 1.00 | ROCK2 (0.48) | ROCK2RECQLGAAP2RX7AR | |
| SCHEMBL29029246 | 0.90 | SMN1; SMN2 (0.49) | ROCK2RECQLP2RX7ALDH1A1POLB | |
| SCHEMBL30403470 | 0.90 | SMN1; SMN2 (0.49) | ROCK2RECQLP2RX7ALDH1A1POLB | |
| SCHEMBL26186442 | 0.86 | ROCK2 (0.49) | ROCK2RECQLP2RX7ALDH1A1POLB | |
| SCHEMBL30285583 | 0.86 | ROCK2 (0.49) | ROCK2RECQLP2RX7ALDH1A1POLB | |
| SCHEMBL30285728 | 0.85 | ROCK2 (0.48) | ROCK2RECQLGAAP2RX7ALDH1A1 | |
| SCHEMBL26186448 | 0.85 | ROCK2 (0.48) | ROCK2RECQLGAAP2RX7ALDH1A1 | |
| SCHEMBL30285857 | 0.81 | SMN1; SMN2 (0.60) | ALDH1A1POLBMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL29005545 | 0.81 | SMN1; SMN2 (0.60) | ALDH1A1POLBMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL30285850 | 0.80 | KCNJ5 (0.57) | ROCK2ALDH1A1POLBP2RX4KCNJ5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115989218-A | Use of N-phenylacetamides having P2X4 receptor antagonistic activity for the treatment of certain eye diseases | 拜耳公司 | 2023-04-18 | — | — | CN | disclosed |