SCHEMBL29005771

SCHEMBL29005771

Br[Mg]Br.COc1cc[c]cc1C

nearest known ligand 0.31

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA4 P22748 1/20 0.31
CA7 P43166 1/20 0.31
CA9 Q16790 1/20 0.31
CA14 Q9ULX7 1/20 0.31
ALOX15 P16050 1/20 0.31
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL76009 0.92
SCHEMBL27638880 0.83 CA2 (0.39) CA12CA1CA2CA4CA7
SCHEMBL27702959 0.78 TSHR (0.32) ACHE
SCHEMBL96297 0.76
SCHEMBL2265976 0.76 HTT (0.47) CA12CA1CA2CA4CA7
SCHEMBL8916738 0.75
SCHEMBL28473248 0.74 L3MBTL1 (0.32) CA12CA1CA2CA4CA7
SCHEMBL27704724 0.74 TDP1 (0.33) CA12CA1CA2CA4CA7
SCHEMBL29180182 0.73 PTPN1 (0.37)
SCHEMBL8674 0.73 CA2 (0.46) CA12CA1CA2CA4CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116139125-A Combination therapy 梅制药公司 2023-05-23 CN disclosed