Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 4/20 | 0.55 |
| ▸ | USP2 | O75604 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10113246 | 0.84 | MAPK1 (0.66) | POLBSMN1; SMN2ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL15196535 | 0.80 | USP2 (0.73) | POLBGAAUSP2SMN1; SMN2TP53 | |
| SCHEMBL2572171 | 0.77 | MAPK1 (0.55) | POLBGAAUSP2ALDH1A1HSD17B10 | |
| SCHEMBL15976544 | 0.73 | POLB (1.00) | POLBGAAUSP2SMN1; SMN2TP53 | |
| SCHEMBL16979450 | 0.73 | DHFR (0.54) | POLBGAASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL19732956 | 0.72 | GAA (0.78) | POLBGAAUSP2TP53ALDH1A1 | |
| SCHEMBL8267885 | 0.72 | GAA (0.78) | POLBGAAUSP2TP53ALDH1A1 | |
| SCHEMBL15574033 | 0.72 | L3MBTL1 (0.65) | POLBGAASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL5173918 | 0.71 | DHFR (0.74) | POLBGAAUSP2SMN1; SMN2TP53 | |
| SCHEMBL14226244 | 0.71 | USP2 (1.00) | POLBGAAUSP2TP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112812066-B | Synthesis method of dihydropyrimidinone compound | 宜春学院 | 2023-04-25 | — | — | CN | disclosed |