Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27645790 | 0.78 | LCK (0.66) | HTTPOLBHPGDLCKKMT2A | |
| SCHEMBL7341189 | 0.77 | PTGER4 (0.58) | HTTPOLBHPGDLCKKMT2A | |
| SCHEMBL289980 | 0.76 | LCK (0.39) | HPGDLCKKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL12284720 | 0.75 | HTT (0.55) | HTTPOLBHPGDLCKKMT2A | |
| SCHEMBL4138460 | 0.74 | POLB (0.67) | POLBHPGDLCKKMT2AMAPT | |
| SCHEMBL15014133 | 0.74 | HTT (0.54) | HTTPOLBHPGDLCKKMT2A | |
| SCHEMBL1274908 | 0.74 | LMNA (0.35) | HTTHPGDMAPTSMN1; SMN2NPC1 | |
| SCHEMBL27813370 | 0.74 | P2RX1 (0.51) | HTTPOLBHPGDLCKKMT2A | |
| SCHEMBL15401797 | 0.72 | MAPT (0.54) | HTTPOLBHPGDLCKKMT2A | |
| SCHEMBL13181149 | 0.72 | L3MBTL1 (0.52) | HTTPOLBHPGDLCKKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427427-A1 | 4 -CYANO- 3 -BENZOYLAMINO-N- PHENYL-BENZAMIDES FOR USE IN PEST CONTROL | Syngenta Participations AG (CH) | 2012-03-14 | — | — | EP | disclosed |