Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 2/20 | 0.64 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | TYR | P14679 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9026552 | 0.78 | CYP2A6 (0.64) | CYP2A6APPRAB9ANPC1MAPK1 | |
| SCHEMBL29502957 | 0.78 | CYP2A6 (1.00) | CYP2A6APPRAB9ANPC1MAPK1 | |
| SCHEMBL17185672 | 0.78 | CYP2A6 (0.64) | CYP2A6APPRAB9ANPC1MAPK1 | |
| SCHEMBL225144 | 0.78 | CYP2A6 (0.64) | CYP2A6APPRAB9ANPC1MAPK1 | |
| SCHEMBL1706926 | 0.78 | CYP2A6 (0.64) | CYP2A6APPRAB9ANPC1MAPK1 | |
| SCHEMBL91009 | 0.78 | CYP2A6 (1.00) | CYP2A6APPRAB9ANPC1MAPK1 | |
| SCHEMBL11396362 | 0.78 | CYP2A6 (0.64) | CYP2A6APPRAB9ANPC1MAPK1 | |
| SCHEMBL9956377 | 0.78 | CYP2A6 (1.00) | CYP2A6APPRAB9ANPC1MAPK1 | |
| SCHEMBL946001 | 0.78 | CYP2A6 (0.58) | CYP2A6APPRAB9ANPC1MAPK1 | |
| SCHEMBL1176914 | 0.75 | CYP2A6 (0.60) | CYP2A6APPRAB9ANPC1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2759543-B1 | CHROMENE COMPOUND AND CURABLE COMPOSITION | TOKUYAMA CORP (JP) | 2017-07-19 | — | — | EP | disclosed |
| US-9487693-B2 | Chromene compound | TOKUYAMA CORPORATION (JP) | 2016-11-08 | — | — | US | disclosed |
| EP-2725017-B1 | CHROMENE COMPOUND | TOKUYAMA CORP (JP) | 2016-06-29 | — | — | EP | disclosed |
| EP-2669277-B1 | CHROMENE COMPOUND | TOKUYAMA CORP (JP) | 2015-07-01 | — | — | EP | disclosed |
| EP-2684886-B1 | CHROMENE COMPOUND | TOKUYAMA CORP (JP) | 2015-06-03 | — | — | EP | disclosed |
| EP-2669278-B1 | CHROMENE COMPOUND | TOKUYAMA CORP (JP) | 2015-05-27 | — | — | EP | disclosed |
| US-8916071-B2 | Chromene compound and curable composition | TOKUYAMA CORPORATION (JP) | 2014-12-23 | — | — | US | disclosed |
| EP-2554624-B1 | PHOTOCHROMIC CURABLE COMPOSITION | TOKUYAMA CORP (JP) | 2014-11-05 | — | — | EP | disclosed |
| US-20140225050-A1 | CHROMENE COMPOUND AND CURABLE COMPOSITION | TOKUYAMA CORPORATION (JP) | 2014-08-14 | — | — | US | disclosed |
| EP-2759543-A1 | CHROMENE COMPOUND AND CURABLE COMPOSITION | Tokuyama Corporation (JP) | 2014-07-30 | — | — | EP | disclosed |
| US-20040237837-A1 | Lightfast additive having UV-absorbing moiety and ink composition including the same | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2004-12-02 | — | — | US | disclosed |
| US-6723859-B2 | BASE STRUCTURE IS A CHROMENE(3,2-A)FLUORENE RING CONTAINING SPIRO-FUSED RINGS; PHOTOCHROMIC LENSES; LARGE FADING RATE, LESS COLOR WHEN DETERIORATED, AND EXCELLENT LIGHT RESISTANCE IN THE PHOTOCHROMIC PROPERTIES | TOKUYAMA CORPORATION (JP) | 2004-04-20 | — | — | US | disclosed |
| US-20040014995-A1 | Chromene compounds | KAWABATA YUICHIRO (JP) | 2004-01-22 | — | — | US | disclosed |
| US-20030096117-A1 | Chromene compound | TOKUYAMA CORPORATION (JP) | 2003-05-22 | — | — | US | disclosed |
| US-6469076-B1 | Chromene compounds | TOKUYAMA CORPORATION (JP) | 2002-10-22 | — | — | US | disclosed |
| EP-1054010-B1 | Chromene compound | TOKUYAMA CORP (JP) | 2002-07-24 | — | — | EP | disclosed |
| EP-1184379-A1 | CHROMENE COMPOUND | TOKUYAMA CORPORATION (JP) | 2002-03-06 | — | — | EP | disclosed |
| US-6340765-B1 | PHOTOCHROMIC DYES AND DEVELOPMENT | TOKUYAMA CORPORATION (JP) | 2002-01-22 | — | — | US | disclosed |
| EP-1116723-A1 | CHROMENE COMPOUNDS | TOKUYAMA CORPORATION (JP) | 2001-07-18 | — | — | EP | disclosed |
| EP-1054010-A1 | Chromene compound | TOKUYAMA CORPORATION (JP) | 2000-11-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040237837-A1 | Lightfast additive having UV-absorbing moiety and ink composition including the same | CDK4, CDKL4, UGT1A4 | CYP2A6 1337/4885APP 3547/4885RAB9A 3228/4885 |
| US-20040014995-A1 | Chromene compounds | SMARCE1, SMARCB1, SMARCA2 | CYP2A6 2241/4885APP 3013/4885RAB9A 2560/4885 |
| US-20140225050-A1 | CHROMENE COMPOUND AND CURABLE COMPOSITION | CRY2, CRY1, CDYL | CYP2A6 798/4885APP 3110/4885RAB9A 3560/4885 |
| US-20030096117-A1 | Chromene compound | SMARCE1, SMARCD2, SMARCB1 | CYP2A6 2342/4885APP 2680/4885RAB9A 2402/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.