Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | FFAR2 | O15552 | 2/20 | 0.43 |
| ▸ | NOS3 | P29474 | 1/20 | 0.42 |
| ▸ | NOS1 | P29475 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3072654 | 0.89 | ADRB2 (0.56) | ADRB2BRD4FFAR2NOS3NOS1 | |
| SCHEMBL141006 | 0.89 | ADRB2 (0.56) | ADRB2BRD4FFAR2NOS3NOS1 | |
| SCHEMBL1253041 | 0.89 | ADRB2 (0.56) | ADRB2BRD4FFAR2NOS3NOS1 | |
| SCHEMBL11308298 | 0.82 | ADRB2 (0.50) | ADRB2BRD4FFAR2NOS3NOS1 | |
| Alcohol SCHEMBL9488915 | 0.80 | ADRB2 (0.48) | ADRB2BRD4FFAR2NOS3NOS1 | |
| SCHEMBL4538085 | 0.78 | ADRB2 (0.58) | ADRB2BRD4FFAR2NOS3NOS1 | |
| SCHEMBL11127234 | 0.77 | ADRB2 (0.45) | ADRB2BRD4FFAR2NOS3NOS1 | |
| SCHEMBL40655 | 0.75 | NOS3 (0.54) | NOS3NOS1TSHRHIF1ATDP1 | |
| SCHEMBL9331652 | 0.75 | NOS3 (0.54) | NOS3NOS1TSHRHIF1ATDP1 | |
| SCHEMBL9331190 | 0.75 | NOS3 (0.54) | NOS3NOS1TSHRHIF1ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7816354-B2 | Oxazolidinone compounds and their use as metabotropic glutamate receptor potentiators | ASTRAZENECA AB (SE) | 2010-10-19 | — | — | US | disclosed |