Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.56 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.45 |
| ▸ | NOS3 | P29474 | 1/20 | 0.45 |
| ▸ | NOS1 | P29475 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3072654 | 1.00 | ADRB2 (0.56) | ADRB2AOC3BRD4TSHRMAPK1 | |
| SCHEMBL1253041 | 1.00 | ADRB2 (0.56) | ADRB2AOC3BRD4TSHRMAPK1 | |
| SCHEMBL11308298 | 0.93 | ADRB2 (0.50) | ADRB2AOC3BRD4TSHRMAPK1 | |
| Alcohol SCHEMBL9488915 | 0.91 | ADRB2 (0.48) | ADRB2AOC3BRD4TSHRMAPK1 | |
| SCHEMBL4538085 | 0.89 | ADRB2 (0.58) | ADRB2AOC3BRD4TSHRMAPK1 | |
| Nitrous Acid SCHEMBL2900769 | 0.89 | ADRB2 (0.46) | ADRB2AOC3BRD4TSHRMAPK1 | |
| SCHEMBL11127234 | 0.87 | ADRB2 (0.45) | ADRB2AOC3BRD4TSHRMAPK1 | |
| SCHEMBL9331652 | 0.85 | NOS3 (0.54) | TSHRHIF1ATDP1NOS3NOS1 | |
| SCHEMBL40655 | 0.85 | NOS3 (0.54) | TSHRHIF1ATDP1NOS3NOS1 | |
| SCHEMBL9331190 | 0.85 | NOS3 (0.54) | TSHRHIF1ATDP1NOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 789 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12540131-B2 | N-(heteroaryl) quinazolin-2-amine derivatives as LRRK2 inhibitors, pharmaceutical compositions, and uses thereof | MERCK SHARP & DOHME LLC (US) | 2026-02-03 | — | — | US | claimed |
| WO-2025053791-A1 | ONE-POT GRAFTING OF POLYMERS FROM ALCOHOLS AND BIOMASSES | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2025-03-13 | — | — | WO | claimed |
| CN-119591964-A | Breathable film containing polystyrene and preparation method thereof | 衢州瑞兴新材料有限责任公司 | 2025-03-11 | — | — | CN | claimed |
| CN-119491240-A | Method for preparing benzyl carboxylic acid compound by taking carbon dioxide as raw material | 哈尔滨工业大学（深圳） | 2025-02-21 | — | — | CN | claimed |
| WO-2024177860-A1 | IN CHEMICO TEST FOR TOXICITY | LEBRUN LABS LLC (US) | 2024-08-29 | — | — | WO | claimed |
| CN-118393009-A | Analysis method of tolote Luo Zhong related substances | 正大制药（青岛）有限公司 | 2024-07-26 | — | — | CN | claimed |
| CN-118165691-A | Sublimation-preventing hot melt adhesive | 浙江澳宇新材料科技有限公司 | 2024-06-11 | — | — | CN | claimed |
| CN-117943084-A | Transition metal catalyst, preparation method and method for preparing organic acid by oxidation and pyrolysis of secondary alcohol | 中国科学院大连化学物理研究所 | 2024-04-30 | — | — | CN | claimed |
| CN-115894273-B | Method for catalyzing alcohol C (OH) -C bond cleavage and functionalization by iodine-doped nonmetallic catalyst | 常州大学 | 2024-04-09 | — | — | CN | claimed |
| CN-114634451-B | Method for synthesizing pyrimidine derivative mediated by t-BuOK | 南京师范大学 | 2023-10-24 | — | — | CN | claimed |
| US-6979829-B2 | Devices and methods for determining the amount of energy absorbed during irradiation | CLEARANT INC. (US) | 2005-12-27 | — | — | US | claimed |
| US-20050245554-A1 | Substituted pyrimidines | MERCK SHARP & DOHME CORP. | 2005-11-03 | — | — | US | claimed |
| EP-1546115-A2 | SUBSTITUTED PYRIMIDINES | Merck & Co., Inc. (US) | 2005-06-29 | — | — | EP | claimed |
| WO-2004029204-A2 | SUBSTITUTED PYRIMIDINES | MERCK & CO., INC. (US) | 2004-04-08 | — | — | WO | claimed |
| US-6613317-B1 | In particular northern corn rootworm | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2003-09-02 | — | — | US | claimed |
| EP-0449975-B1 | NON-TIN-BASED, LOW TOXICITY ANTI-FOULING AGENTS | BATTELLE MEMORIAL INSTITUTE (US) | 1997-04-23 | — | — | EP | claimed |
| US-5441743-A | In thermoplastic or thermosetting binder | BATTELLE MEMORIAL INSTITUTE (US) | 1995-08-15 | — | — | US | claimed |
| WO-1990006975-A1 | NON-TIN-BASED, LOW TOXICITY ANTI-FOULING AGENTS | BATTELLE MEMORIAL INSTITUTE (US) | 1990-06-28 | — | — | WO | claimed |
| EP-0122151-B1 | PRODUCTION OF PRIMARY OR SECONDARY ALCOHOL DERIVATIVES OF PHOSPHOLIPIDS BY THE ENZYMATIC TECHNIQUE | MEITO SANGYO KABUSHIKI KAISHA (JP) | 1989-02-15 | — | — | EP | claimed |
| EP-0251369-A2 | Pharmaceutical compositions endowed with sequestering activity for the biliary acids, containing colestyramin as their active principle, and process for preparing them | FARKEMO S.r.l. (IT) | 1988-01-07 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12540131-B2 | N-(heteroaryl) quinazolin-2-amine derivatives as LRRK2 inhibitors, pharmaceutical compositions, and uses thereof | LRRK2, PARK7, SNCA | ADRB2 303/4885AOC3 477/4885BRD4 1279/4885 |
| US-20050245554-A1 | Substituted pyrimidines | CNR1, CNR2, GPR119 | ADRB2 229/4885AOC3 1075/4885BRD4 587/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.