Phenol

Phenol

SCHEMBL29008157

O=C1OCCO1.Oc1ccccc1.Oc1ccccc1

nearest known ligand 0.52

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.52
CA12 O43570 1/20 0.52
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
GLA P06280 1/20 0.52
CA3 P07451 1/20 0.52
CA4 P22748 1/20 0.52
CA9 Q16790 1/20 0.52
CA14 Q9ULX7 1/20 0.52
KMT2A Q03164 1/20 0.40
ITGB2 P05107 1/20 0.40
ICAM1 P05362 1/20 0.40
ITGAL P20701 1/20 0.40
MMP3 P08254 1/20 0.39
BCL2L1 Q07817 1/20 0.39
CES2 O00748 1/20 0.38
MMP2 P08253 1/20 0.37
DBH P09172 1/20 0.37
ESR1 P03372 3/20 0.37
ESR2 Q92731 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenol SCHEMBL27865185 1.00 TDP1 (0.52) TDP1CA12CA1CA2GLA
Benzene SCHEMBL11037142 0.82 ITGB2 (0.40) CA1CA9KMT2AITGB2ICAM1
Biphenyl SCHEMBL28053336 0.80 ALDH1A1 (0.47) KMT2AITGB2ICAM1ITGALLMNA
Phenol SCHEMBL1696496 0.76 CA12 (0.69) TDP1CA12CA1CA2GLA
Phenol SCHEMBL28190193 0.76 CA12 (0.69) TDP1CA12CA1CA2GLA
Phenol SCHEMBL10524954 0.76 CA12 (0.69) TDP1CA12CA1CA2GLA
Phenol SCHEMBL9542177 0.76 CA12 (0.69) TDP1CA12CA1CA2GLA
Phenol SCHEMBL978674 0.76 CA12 (0.69) TDP1CA12CA1CA2GLA
Phenol SCHEMBL37047 0.76 CA12 (0.69) TDP1CA12CA1CA2GLA
Toluene SCHEMBL6404501 0.76 LMNA (0.52) KMT2AITGB2ICAM1ITGALCES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115819190-A Preparation method of light-colored aromatic diol chain extender 江苏湘园化工有限公司 2023-03-21 CN disclosed