Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.40 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.40 |
| ▸ | ITGAL | P20701 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | CRHBP | P24387 | 2/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.35 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.35 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| O-Xylene SCHEMBL29032311 | 0.83 | TSHR (0.50) | LMNATSHRACHEITGB2ICAM1 | |
| Benzene SCHEMBL11037142 | 0.82 | ITGB2 (0.40) | LMNATSHRITGB2ICAM1ITGAL | |
| Biphenyl SCHEMBL28053336 | 0.80 | ALDH1A1 (0.47) | LMNAITGB2ICAM1ITGALSMN1; SMN2 | |
| Toluene SCHEMBL11325304 | 0.76 | LMNA (0.69) | LMNATSHRALOX12ACHEITGB2 | |
| Phenol SCHEMBL29008157 | 0.76 | TDP1 (0.52) | LMNAITGB2ICAM1ITGALCES2 | |
| Toluene SCHEMBL28081861 | 0.76 | ACHE (0.92) | LMNATSHRALOX12ACHECES2 | |
| Toluene SCHEMBL11878868 | 0.76 | — | — | |
| Toluene SCHEMBL27965308 | 0.76 | ACHE (0.92) | LMNATSHRALOX12ACHECES2 | |
| Toluene SCHEMBL282478 | 0.76 | — | — | |
| Toluene SCHEMBL6746582 | 0.76 | ACHE (0.92) | LMNATSHRALOX12ACHECES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6930151-B2 | Star block copolymers comprising polyisobutylene-B-polyacrylonitrile arms radiating from an aromatic core | UNIVERSITY OF AKRON (US) | 2005-08-16 | — | — | US | disclosed |
| US-20030236354-A1 | Star block copolymers comprising polyisobutylene-B-polyacrylonitrile arms radiating from an aromatic core | AKRON, THE UNIVERSITY OF | 2003-12-25 | — | — | US | disclosed |