Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3665656 | 0.82 | ALDH1A1 (0.46) | LMNAKEAP1ALDH1A1SMN1; SMN2CA7 | |
| SCHEMBL28390937 | 0.80 | ALOX15 (0.47) | LMNAALDH1A1AKR1B1FFAR1SMN1; SMN2 | |
| SCHEMBL117263 | 0.78 | ALDH1A1 (0.45) | ALDH1A1MAPK1CA4CA6CA5A | |
| Benzene SCHEMBL10445518 | 0.78 | ALDH1A1 (0.45) | ALDH1A1MAPK1CA4CA6CA5A | |
| SCHEMBL28493287 | 0.76 | TRPV6 (0.41) | ALDH1A1MAPK1SMN1; SMN2CA4CA6 | |
| SCHEMBL1275435 | 0.76 | PCSK9 (0.47) | LMNAALDH1A1MAPK1SLC6A3SMN1; SMN2 | |
| SCHEMBL25431949 | 0.76 | ORAI1 (0.37) | ALDH1A1MAPK1SMN1; SMN2CA4CA6 | |
| SCHEMBL29014483 | 0.74 | CA1 (0.47) | LMNAALDH1A1FFAR1MAPK1CA4 | |
| SCHEMBL1491911 | 0.74 | PCSK9 (0.41) | ALDH1A1MAPK1CA4CA6CA5A | |
| SCHEMBL28088282 | 0.74 | FFAR1 (0.42) | LMNAKEAP1NR4A2FFAR1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116209722-A | Near infrared cyanine dyes and conjugates thereof | 伯拉考成像股份公司 | 2023-06-02 | — | — | CN | disclosed |