Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL717072 | 0.98 | EGLN3 (0.32) | EGLN3SMN1; SMN2KDM4EPOLBMEN1 | |
| Bromide SCHEMBL571256 | 0.96 | MEN1 (0.33) | EGLN3SMN1; SMN2KDM4EPOLBMEN1 | |
| Hydrochloric Acid SCHEMBL6115678 | 0.89 | TBXAS1 (0.36) | EGLN3SMN1; SMN2TBXAS1KDM4EMEN1 | |
| SCHEMBL35213 | 0.87 | LMNA (0.34) | SMN1; SMN2TBXAS1KDM4EMEN1HSP90AA1 | |
| SCHEMBL18211781 | 0.84 | TSHR (0.40) | TBXAS1MEN1KMT2A | |
| SCHEMBL18211773 | 0.84 | TSHR (0.40) | TBXAS1MEN1KMT2A | |
| SCHEMBL22916707 | 0.84 | TSHR (0.40) | TBXAS1MEN1KMT2A | |
| SCHEMBL4249049 | 0.83 | MEN1 (0.37) | SMN1; SMN2MEN1HSP90AA1KMT2A | |
| Bromide SCHEMBL1977150 | 0.83 | TSHR (0.39) | TBXAS1MEN1KMT2A | |
| SCHEMBL29002029 | 0.81 | MEN1 (0.30) | SMN1; SMN2MEN1HSP90AA1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115820294-A | Method for removing oxygen-containing compounds in Fischer-Tropsch synthetic oil | 国家能源集团宁夏煤业有限责任公司 | 2023-03-21 | — | — | CN | disclosed |