Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | APAF1 | O14727 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.47 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | FDPS | P14324 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL717073 | 0.98 | SMN1; SMN2 (0.49) | SMN1; SMN2MAPK1MEN1HSP90AA1KMT2A | |
| Bromide SCHEMBL571258 | 0.96 | SMN1; SMN2 (0.51) | SMN1; SMN2MAPK1MEN1HSP90AA1KMT2A | |
| SCHEMBL4249046 | 0.83 | SMN1; SMN2 (0.49) | SMN1; SMN2MAPK1MEN1HSP90AA1KMT2A | |
| Bromide SCHEMBL6114995 | 0.83 | SMN1; SMN2 (0.63) | SMN1; SMN2MAPK1MEN1HSP90AA1KMT2A | |
| Bromide SCHEMBL1977149 | 0.83 | SMN1; SMN2 (0.63) | SMN1; SMN2MAPK1MEN1HSP90AA1KMT2A | |
| SCHEMBL28513046 | 0.82 | SMN1; SMN2 (0.49) | SMN1; SMN2MAPK1MEN1HSP90AA1KMT2A | |
| SCHEMBL3675843 | 0.81 | SMN1; SMN2 (0.36) | SMN1; SMN2MAPK1MEN1HSP90AA1KMT2A | |
| Hydrochloric Acid SCHEMBL28435491 | 0.81 | SMN1; SMN2 (0.51) | SMN1; SMN2MAPK1MEN1HSP90AA1KMT2A | |
| Succinic Acid SCHEMBL29142255 | 0.80 | SMN1; SMN2 (0.47) | SMN1; SMN2MAPK1MEN1HSP90AA1KMT2A | |
| Glutarate SCHEMBL29142331 | 0.80 | SMN1; SMN2 (0.64) | SMN1; SMN2MAPK1MEN1HSP90AA1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115820294-A | Method for removing oxygen-containing compounds in Fischer-Tropsch synthetic oil | 国家能源集团宁夏煤业有限责任公司 | 2023-03-21 | — | — | CN | disclosed |