SCHEMBL717073

SCHEMBL717073

C[n+]1ccn(CCC(=O)O)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.49
MEN1 O00255 3/20 0.49
KMT2A Q03164 3/20 0.49
HSP90AA1 P07900 2/20 0.49
MAPK1 P28482 2/20 0.49
APAF1 O14727 1/20 0.49
NPC1 O15118 1/20 0.49
PLA2G1B P04054 1/20 0.49
MAPT P10636 1/20 0.49
HTT P42858 1/20 0.49
RAB9A P51151 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49
ATG4B Q9Y4P1 1/20 0.49
LMNA P02545 3/20 0.43
EGLN3 Q9H6Z9 2/20 0.43
FDPS P14324 2/20 0.41
THRB P10828 1/20 0.35
HPGD P15428 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL571258 0.98 SMN1; SMN2 (0.51) SMN1; SMN2MEN1KMT2AHSP90AA1MAPK1
Hydrochloric Acid SCHEMBL29008265 0.98 SMN1; SMN2 (0.47) SMN1; SMN2MEN1KMT2AHSP90AA1MAPK1
SCHEMBL4249046 0.85 SMN1; SMN2 (0.49) SMN1; SMN2MEN1KMT2AHSP90AA1MAPK1
Bromide SCHEMBL1977149 0.84 SMN1; SMN2 (0.63) SMN1; SMN2MEN1KMT2AHSP90AA1MAPK1
Bromide SCHEMBL6114995 0.84 SMN1; SMN2 (0.63) SMN1; SMN2MEN1KMT2AHSP90AA1MAPK1
SCHEMBL28513046 0.83 SMN1; SMN2 (0.49) SMN1; SMN2MEN1KMT2AHSP90AA1MAPK1
SCHEMBL3675843 0.83 SMN1; SMN2 (0.36) SMN1; SMN2MEN1KMT2AHSP90AA1MAPK1
Glutarate SCHEMBL29142331 0.82 SMN1; SMN2 (0.64) SMN1; SMN2MEN1KMT2AHSP90AA1MAPK1
Succinic Acid SCHEMBL29142255 0.82 SMN1; SMN2 (0.47) SMN1; SMN2MEN1KMT2AHSP90AA1MAPK1
SCHEMBL12682672 0.80 SMN1; SMN2 (0.53) SMN1; SMN2MEN1KMT2AHSP90AA1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9999217-B2 Compositions for stabilizing DNA, RNA, and proteins in blood and other biological samples during shipping and storage at ambient temperatures BIOMATRICA, INC. (US) 2018-06-19 US claimed
EP-2598661-B1 COMPOSITIONS FOR STABILIZING DNA, RNA AND PROTEINS IN SALIVA AND OTHER BIOLOGICAL SAMPLES DURING SHIPPING AND STORAGE AT AMBIENT TEMPERATURES BIOMATRICA INC (US) 2017-09-27 EP claimed
EP-2598660-B1 COMPOSITIONS FOR STABILIZING DNA, RNA AND PROTEINS IN BLOOD AND OTHER BIOLOGICAL SAMPLES DURING SHIPPING AND STORAGE AT AMBIENT TEMPERATURES BIOMATRICA INC (US) 2017-03-15 EP claimed
EP-1698686-B1 Co-Production of olefins and esters via ethenolysis of unsaturated fats in non-aqueous ionic liquids. INST FRANCAIS DU PETROLE (FR) 2012-11-07 EP claimed
EP-1810961-B1 Method of co-producing olefins and diesters or diacids by homometathesis of unsaturated fatty bodies in non-aqueous ionic liquids INST FRANCAIS DU PETROLE (FR) 2010-12-29 EP claimed
US-7754904-B2 Process for co-producing olefins and diesters or diacids by homomethathesis of unsaturated fats in non-aqueous ionic liquids INSTITUT FRANCAIS DU PETROLE (FR) 2010-07-13 US claimed
US-7678932-B2 Process for co-producing olefins and esters by ethenolysis of unsaturated fats in non-aqueous ionic liquids INSTITUT FRANCAIS DU PETROLE (FR) 2010-03-16 US claimed
US-20070179302-A1 PROCESS FOR CO-PRODUCING OLEFINS AND DIESTERS OR DIACIDS BY HOMOMETHATHESIS OF UNSATURATED FATS IN NON-AQUEOUS IONIC LIQUIDS INSTITUT FRANCAIS DU PETROLE (FR) 2007-08-02 US claimed
US-20060079704-A1 Process for co-producing olefins and esters by ethenolysis of unsaturated fats in non-aqueous ionic liquids INSTITUT FRANCAIS DU PETROLE (FR) 2006-04-13 US claimed
US-20060070919-A1 Process for separating oxygen-containing compounds contained in a hydrocarbon feed, employing an ionic liquid INSTITUT FRANCAIS DU PETROLE (FR) 2006-04-06 US claimed
US-9999217-B2 Compositions for stabilizing DNA, RNA, and proteins in blood and other biological samples during shipping and storage at ambient temperatures BIOMATRICA, INC. (US) 2018-06-19 US disclosed
US-20160338342-A1 COMPOSITIONS FOR STABILIZING DNA, RNA AND PROTEINS IN BLOOD AND OTHER BIOLOGICAL SAMPLES DURING SHIPPING AND STORAGE AT AMBIENT TEMPERATURES EXACT SCIENCES CORPORATION 2016-11-24 US disclosed
US-9376709-B2 Compositions for stabilizing DNA and RNA in blood and other biological samples during shipping and storage at ambient temperatures BIOMATRICA, INC. (US) 2016-06-28 US disclosed
US-8598378-B2 Methods and compositions for extraction and transesterification of biomass components UNIVERSITY OF HAWAII (US) 2013-12-03 US disclosed
US-20120052572-A1 COMPOSITIONS FOR STABILIZING DNA, RNA AND PROTEINS IN BLOOD AND OTHER BIOLOGICAL SAMPLES DURING SHIPPING AND STORAGE AT AMBIENT TEMPERATURES EXACT SCIENCES CORPORATION 2012-03-01 US disclosed
WO-2009114830-A2 METHODS AND COMPOSITIONS FOR EXTRACTION AND TRANSESTERIFICATION OF BIOMASS COMPONENTS UNIVERSITY OF HAWAII (US) 2009-09-17 WO disclosed
US-20090234146-A1 METHODS AND COMPOSITIONS FOR EXTRACTION AND TRANSESTERIFICATION OF BIOMASS COMPONENTS UNIVERSITY OF HAWAII (US) 2009-09-17 US disclosed
US-20070179302-A1 PROCESS FOR CO-PRODUCING OLEFINS AND DIESTERS OR DIACIDS BY HOMOMETHATHESIS OF UNSATURATED FATS IN NON-AQUEOUS IONIC LIQUIDS INSTITUT FRANCAIS DU PETROLE (FR) 2007-08-02 US disclosed
US-20060079704-A1 Process for co-producing olefins and esters by ethenolysis of unsaturated fats in non-aqueous ionic liquids INSTITUT FRANCAIS DU PETROLE (FR) 2006-04-13 US disclosed
US-20060070919-A1 Process for separating oxygen-containing compounds contained in a hydrocarbon feed, employing an ionic liquid INSTITUT FRANCAIS DU PETROLE (FR) 2006-04-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070179302-A1 PROCESS FOR CO-PRODUCING OLEFINS AND DIESTERS OR DIACIDS BY HOMOMETHATHESIS OF UNSATURATED FATS IN NON-AQUEOUS IONIC LIQUIDS FADS2, SCD, FADS1 SMN1; SMN2 4192/4885MEN1 3705/4885KMT2A 4309/4885
US-20160338342-A1 COMPOSITIONS FOR STABILIZING DNA, RNA AND PROTEINS IN BLOOD AND OTHER BIOLOGICAL SAMPLES DURING SHIPPING AND STORAGE AT AMBIENT TEMPERATURES HNRNPD, HNRNPDL, HNRNPL SMN1; SMN2 422/4885MEN1 3064/4885KMT2A 3136/4885
US-20120052572-A1 COMPOSITIONS FOR STABILIZING DNA, RNA AND PROTEINS IN BLOOD AND OTHER BIOLOGICAL SAMPLES DURING SHIPPING AND STORAGE AT AMBIENT TEMPERATURES HNRNPD, HNRNPDL, HNRNPL SMN1; SMN2 422/4885MEN1 3064/4885KMT2A 3136/4885
US-20060079704-A1 Process for co-producing olefins and esters by ethenolysis of unsaturated fats in non-aqueous ionic liquids ELOVL3, ELOVL1, FASN SMN1; SMN2 4052/4885MEN1 2671/4885KMT2A 4614/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.