Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRN | P28799 | 7/20 | 0.76 |
| ▸ | SORT1 | Q99523 | 7/20 | 0.76 |
| ▸ | KLKB1 | P03952 | 4/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24283549 | 0.86 | GRN (1.00) | GRNSORT1KDM4E | |
| SCHEMBL4134838 | 0.86 | GRN (0.74) | GRNSORT1KLKB1POLBTSHR | |
| SCHEMBL10447771 | 0.80 | GRN (0.51) | GRNSORT1KLKB1POLBTSHR | |
| SCHEMBL28943994 | 0.77 | CNR1 (0.50) | GRNSORT1KLKB1POLBTSHR | |
| SCHEMBL24283490 | 0.77 | GRN (0.67) | GRNSORT1POLBKDM4EMEN1 | |
| SCHEMBL29478786 | 0.76 | SORT1 (0.57) | GRNSORT1KLKB1POLBTSHR | |
| SCHEMBL22637715 | 0.76 | SORT1 (0.57) | GRNSORT1KLKB1POLBTSHR | |
| SCHEMBL950947 | 0.76 | GRN (0.49) | GRNSORT1KLKB1POLBTSHR | |
| SCHEMBL22637837 | 0.76 | GRN (0.51) | GRNSORT1KLKB1POLBTSHR | |
| SCHEMBL22637870 | 0.76 | TP53 (0.50) | GRNSORT1KLKB1POLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115836062-A | Compound and medical application thereof | 心悦生医股份有限公司 | 2023-03-21 | — | — | CN | disclosed |