SCHEMBL29009228

SCHEMBL29009228

CCN(CC)C(=S)Sc1ccc(-c2ccccc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.50
NPC1 O15118 2/20 0.50
RAB9A P51151 2/20 0.50
ALDH1A1 P00352 10/20 0.49
HPGD P15428 4/20 0.49
MAPT P10636 3/20 0.49
MGLL Q99685 4/20 0.47
GAA P10253 3/20 0.42
LMNA P02545 3/20 0.41
PKM P14618 3/20 0.41
HTT P42858 2/20 0.41
AGTR1 P30556 2/20 0.41
PHGDH O43175 2/20 0.41
NFKB1 P19838 2/20 0.41
PLIN1 O60240 1/20 0.41
GMNN O75496 1/20 0.41
TRPA1 O75762 1/20 0.41
ABCB11 O95342 1/20 0.41
TP53 P04637 1/20 0.41
ALDH2 P05091 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5299279 0.89 SMN1; SMN2 (0.56) SMN1; SMN2NPC1RAB9AALDH1A1HPGD
SCHEMBL27521010 0.87 SMN1; SMN2 (0.54) SMN1; SMN2NPC1RAB9AALDH1A1HPGD
SCHEMBL31364230 0.80 ALDH1A1 (0.45) SMN1; SMN2NPC1RAB9AALDH1A1HPGD
Biphenyl SCHEMBL27941670 0.77 SMN1; SMN2 (0.55) SMN1; SMN2NPC1RAB9AALDH1A1HPGD
SCHEMBL19468041 0.77 SMN1; SMN2 (0.51) SMN1; SMN2NPC1RAB9AALDH1A1HPGD
SCHEMBL11820071 0.75 ALDH1A1 (0.54) SMN1; SMN2NPC1RAB9AALDH1A1HPGD
SCHEMBL711232 0.75 ALDH1A1 (0.39) SMN1; SMN2NPC1RAB9AALDH1A1HPGD
SCHEMBL27649469 0.74 PKM (0.55) SMN1; SMN2NPC1RAB9AALDH1A1MAPT
SCHEMBL9872134 0.72 ALDH1A1 (0.53) SMN1; SMN2NPC1RAB9AALDH1A1HPGD
SCHEMBL27961635 0.71 ALDH1A1 (0.42) SMN1; SMN2NPC1RAB9AALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116217459-A Xanthate derivatization reagent and preparation method and application thereof 西北大学 2023-06-06 CN disclosed