Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 5/20 | 0.40 |
| ▸ | MGLL | Q99685 | 2/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27629377 | 0.98 | ALDH1A1 (0.52) | ALDH1A1ALDH2PKMGAAHPGD | |
| SCHEMBL27649476 | 0.92 | MGLL (0.47) | ALDH1A1ALDH2PKMMGLLNPC1 | |
| SCHEMBL27629381 | 0.92 | MGLL (0.47) | ALDH1A1ALDH2PKMMGLLNPC1 | |
| SCHEMBL27649554 | 0.92 | MGLL (0.47) | ALDH1A1ALDH2PKMMGLLNPC1 | |
| SCHEMBL27649575 | 0.92 | MGLL (0.47) | ALDH1A1ALDH2PKMMGLLNPC1 | |
| SCHEMBL27629390 | 0.92 | MGLL (0.47) | ALDH1A1ALDH2PKMMGLLNPC1 | |
| SCHEMBL6884022 | 0.91 | ALDH1A1 (0.59) | ALDH1A1ALDH2PKMGAAHPGD | |
| SCHEMBL27649469 | 0.88 | PKM (0.55) | ALDH1A1ALDH2PKMGAALMNA | |
| SCHEMBL6884025 | 0.84 | ALDH1A1 (0.55) | ALDH1A1ALDH2PKMGAAHPGD | |
| SCHEMBL5299279 | 0.82 | SMN1; SMN2 (0.56) | ALDH1A1ALDH2PKMGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4225682-A | PEPTIZED | DENKA CHEMICAL CORPORATION (US) | 1980-09-30 | — | — | US | claimed |
| US-5019611-A | Tetrahydrotriazinethiones | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1991-05-28 | — | — | US | disclosed |
| EP-0278890-A2 | Non-staining and slightly-staining antiozonants | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1988-08-17 | — | — | EP | disclosed |
| US-4250083-A | A STYRENATED DIPHENYLAMINE PRESENT DURING EMULSION POLYMERIZATION FOLLOWED BY PEPTIZATION; STORAGE STABILITY | DENKA CHEMICAL CORPORATION (US) | 1981-02-10 | — | — | US | disclosed |
| US-4225682-A | PEPTIZED | DENKA CHEMICAL CORPORATION (US) | 1980-09-30 | — | — | US | disclosed |