Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | CTSG | P08311 | 1/20 | 0.39 |
| ▸ | CMA1 | P23946 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | EEF2K | O00418 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9633894 | 0.78 | KMT2A (0.73) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL29009447 | 0.78 | MEN1 (0.50) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL161783 | 0.71 | HTR6 (0.61) | MAPTCYP19A1CA1CA2CA12 | |
| SCHEMBL30434773 | 0.71 | KMT2A (0.61) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL7471475 | 0.68 | CA1 (0.48) | KMT2AMAPTCYP19A1CA1CA2 | |
| Benzonitrile SCHEMBL6899297 | 0.67 | TSHR (0.67) | MAPTCYP19A1CA1CA2CA12 | |
| Benzonitrile SCHEMBL4710240 | 0.67 | TSHR (0.67) | MAPTCYP19A1CA1CA2CA12 | |
| SCHEMBL8514633 | 0.66 | CA2 (0.59) | MAPTCYP19A1ALDH1A1LMNACA1 | |
| SCHEMBL1794540 | 0.66 | CA1 (0.46) | KMT2AMAPTCYP19A1CA1CA2 | |
| SCHEMBL23046650 | 0.65 | TSHR (0.93) | MAPTALDH1A1LMNACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116178229-B | N-acyl sulfilimine compound and preparation method thereof | 石河子大学 | 2024-03-15 | — | — | CN | disclosed |
| CN-116178229-A | N-acyl sulfilimine compound and preparation method thereof | 石河子大学 | 2023-05-30 | — | — | CN | disclosed |