Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 3/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29009559 | 0.83 | MAPK1 (0.47) | HRH1KCNH2CYP2D6CYP3A4 | |
| SCHEMBL29009534 | 0.80 | HRH1 (0.37) | HRH1KCNH2CYP2D6CYP3A4HDAC1 | |
| SCHEMBL29009535 | 0.80 | HRH1 (0.35) | HRH1KCNH2CYP2D6CYP3A4HDAC1 | |
| SCHEMBL29009504 | 0.72 | PDPK1 (0.41) | — | |
| SCHEMBL29009499 | 0.72 | AURKA (0.42) | — | |
| SCHEMBL29009516 | 0.69 | EGFR (0.35) | HRH1KCNH2CYP2D6CYP3A4HDAC1 | |
| SCHEMBL29009502 | 0.64 | PDPK1 (0.63) | — | |
| SCHEMBL30382285 | 0.64 | PDPK1 (0.63) | — | |
| SCHEMBL30382244 | 0.62 | PDPK1 (0.42) | — | |
| SCHEMBL29009491 | 0.62 | PDPK1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116217551-A | Substituted indazole or azaindazole compounds and application thereof | 河南中医药大学 | 2023-06-06 | — | — | CN | claimed |
| CN-116217551-A | Substituted indazole or azaindazole compounds and application thereof | 河南中医药大学 | 2023-06-06 | — | — | CN | disclosed |