Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | FLT1 | P17948 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29009558 | 0.83 | MAPK3 (0.48) | PDPK1 | |
| SCHEMBL29009533 | 0.81 | DRD2 (0.40) | PDPK1FGFR1FLT1DRD2DRD3 | |
| SCHEMBL30382244 | 0.79 | PDPK1 (0.42) | PDPK1FGFR1FLT1 | |
| SCHEMBL29009491 | 0.79 | PDPK1 (0.42) | PDPK1FGFR1FLT1 | |
| SCHEMBL29009502 | 0.78 | PDPK1 (0.63) | PDPK1FGFR1FLT1 | |
| SCHEMBL30382285 | 0.78 | PDPK1 (0.63) | PDPK1FGFR1FLT1 | |
| SCHEMBL29009493 | 0.74 | FGFR1 (0.59) | PDPK1FGFR1FLT1 | |
| SCHEMBL29009507 | 0.72 | HRH1 (0.32) | — | |
| SCHEMBL29009514 | 0.70 | — | — | |
| SCHEMBL28401037 | 0.65 | PDGFRB (0.47) | FGFR1FLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116217551-A | Substituted indazole or azaindazole compounds and application thereof | 河南中医药大学 | 2023-06-06 | — | — | CN | claimed |
| CN-116217551-A | Substituted indazole or azaindazole compounds and application thereof | 河南中医药大学 | 2023-06-06 | — | — | CN | disclosed |