Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.46 |
| ▸ | PLK1 | P53350 | 1/20 | 0.45 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | CDC25B | P30305 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GMNN | O75496 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9303595 | 0.78 | POLB (0.60) | SIGMAR1NR4A1NR4A2NR4A3PLK1 | |
| SCHEMBL10407111 | 0.77 | NR4A1 (0.59) | SIGMAR1NR4A1NR4A2NR4A3PLK1 | |
| SCHEMBL8174124 | 0.76 | TSHR (0.56) | SIGMAR1NR4A1NR4A2NR4A3PLK1 | |
| SCHEMBL9480890 | 0.74 | NR4A1 (0.55) | SIGMAR1NR4A1NR4A2NR4A3PLK1 | |
| SCHEMBL31276830 | 0.74 | RAB9A (0.46) | KMT2AALDH1A1KDM4ELMNAHPGD | |
| SCHEMBL8376485 | 0.73 | NR4A1 (0.59) | SIGMAR1NR4A1NR4A2NR4A3PLK1 | |
| SCHEMBL29009650 | 0.73 | PLAU (0.49) | PTPN1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL3808036 | 0.72 | NR4A1 (0.45) | SIGMAR1NR4A1NR4A2NR4A3PLK1 | |
| SCHEMBL14855476 | 0.71 | NR4A1 (0.52) | SIGMAR1NR4A1NR4A2NR4A3PLK1 | |
| SCHEMBL18652132 | 0.71 | NR4A1 (0.52) | SIGMAR1NR4A1NR4A2NR4A3PLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115010564-B | Preparation method of o-iodophenyl compound | 苏州大学 | 2024-03-19 | — | — | CN | disclosed |
| CN-115010564-A | Preparation method of o-iodophenyl compound | 苏州大学 | 2022-09-06 | — | — | CN | disclosed |