Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.56 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.56 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | CDC25B | P30305 | 1/20 | 0.50 |
| ▸ | PLK1 | P53350 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MMP3 | P08254 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9001638 | 0.83 | POLB (0.75) | POLBMAOBKMT2AKDM4EHTT | |
| SCHEMBL9548533 | 0.82 | NR4A1 (0.60) | NR4A1NR4A2NR4A3KMT2AMEN1 | |
| SCHEMBL10969110 | 0.82 | LDHA (0.60) | POLBMAOBKMT2AMEN1PLAU | |
| SCHEMBL10407111 | 0.82 | NR4A1 (0.59) | POLBNR4A1NR4A2NR4A3KMT2A | |
| SCHEMBL11833560 | 0.81 | NR4A1 (0.58) | NR4A1NR4A2NR4A3KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL11683665 | 0.79 | NR4A1 (0.56) | POLBNR4A1NR4A2NR4A3KMT2A | |
| Hydrochloric Acid SCHEMBL11865419 | 0.79 | NR4A1 (0.56) | NR4A1NR4A2NR4A3KMT2AMEN1 | |
| SCHEMBL29009647 | 0.78 | SIGMAR1 (0.46) | POLBNR4A1NR4A2NR4A3KMT2A | |
| SCHEMBL3792155 | 0.77 | NR4A1 (0.53) | POLBNR4A1NR4A2NR4A3KMT2A | |
| SCHEMBL31060098 | 0.77 | NR4A1 (0.53) | POLBNR4A1NR4A2NR4A3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8410303-B2 | Direct conversion of phenols into amides and esters of benzoic acid | The Florida State University Research Foundation, Inc. (US) | 2013-04-02 | — | — | US | disclosed |
| US-5278315-A | Phenylaminonaphthalyl hydrazone | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-01-11 | — | — | US | disclosed |