Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.53 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.53 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.53 |
| ▸ | PLK1 | P53350 | 1/20 | 0.51 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.49 |
| ▸ | MMP3 | P08254 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | CDC25B | P30305 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4079233 | 0.87 | ALOX5 (0.49) | TSHRNR4A1NR4A2NR4A3PLK1 | |
| SCHEMBL11583886 | 0.80 | NR4A1 (0.47) | TSHRNR4A1NR4A2NR4A3PLK1 | |
| SCHEMBL16223357 | 0.80 | NR4A1 (0.46) | TSHRNR4A1NR4A2NR4A3PLK1 | |
| SCHEMBL10407111 | 0.79 | NR4A1 (0.59) | TSHRNR4A1NR4A2NR4A3PLK1 | |
| SCHEMBL28922355 | 0.78 | WDR5 (0.68) | TSHRNR4A1NR4A2NR4A3PTPN1 | |
| SCHEMBL5716814 | 0.77 | NR4A1 (0.61) | TSHRNR4A1NR4A2NR4A3PLK1 | |
| SCHEMBL32665708 | 0.77 | NR4A1 (0.61) | TSHRNR4A1NR4A2NR4A3PLK1 | |
| SCHEMBL2230795 | 0.77 | NR4A1 (0.61) | TSHRNR4A1NR4A2NR4A3PLK1 | |
| SCHEMBL9480890 | 0.76 | NR4A1 (0.55) | TSHRNR4A1NR4A2NR4A3PLK1 | |
| SCHEMBL29009647 | 0.76 | SIGMAR1 (0.46) | TSHRNR4A1NR4A2NR4A3PLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000056691-A1 | SYNTHESIS OF VAPOL LIGANDS | ARCH DEVELOPMENT CORPORATION (US) | 2000-09-28 | — | — | WO | disclosed |