Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | PPARA | Q07869 | 8/20 | 0.48 |
| ▸ | PPARG | P37231 | 5/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 5/20 | 0.43 |
| ▸ | FABP2 | P12104 | 2/20 | 0.42 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 4/20 | 0.41 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29009673 | 0.79 | POLB (0.56) | CYP3A4CYP2C19KMT2AMEN1CYP2C9 | |
| SCHEMBL1951077 | 0.77 | CYP1A2 (0.43) | LMNACYP1A2CYP3A4CYP2C19MAPT | |
| SCHEMBL29009677 | 0.76 | POLB (0.44) | CYP2C19KMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL12545455 | 0.76 | LMNA (0.39) | LMNAPPARAPPARGCYP1A2CYP3A4 | |
| SCHEMBL29837172 | 0.76 | LMNA (0.39) | LMNAPPARAPPARGCYP1A2CYP3A4 | |
| SCHEMBL29009671 | 0.75 | POLB (0.43) | MAPTKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL30758070 | 0.73 | AKT1 (0.47) | — | |
| SCHEMBL11448992 | 0.71 | PPARA (0.62) | LMNAPPARAPPARGCYP1A2CYP3A4 | |
| SCHEMBL11569812 | 0.69 | PPARA (0.62) | LMNAPPARAPPARGCYP1A2CYP3A4 | |
| SCHEMBL1951078 | 0.68 | HTT (0.43) | LMNACYP1A2CYP3A4CYP2C19MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115010564-B | Preparation method of o-iodophenyl compound | 苏州大学 | 2024-03-19 | — | — | CN | disclosed |
| CN-115010564-A | Preparation method of o-iodophenyl compound | 苏州大学 | 2022-09-06 | — | — | CN | disclosed |