SCHEMBL29009685

SCHEMBL29009685

CCC[Si](CCC)(N(C)C(C)=O)N(C)C(C)=O

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.36
CES1 P23141 2/20 0.32
CES2 O00748 1/20 0.31
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31114550 0.80 ALDH1A1 (0.31) ALDH1A1TDP1
SCHEMBL11329616 0.79 ALDH1A1 (0.33) ALDH1A1TDP1
SCHEMBL31114562 0.78 ALDH1A1 (0.30) ALDH1A1
SCHEMBL29009674 0.73 CHRM2 (0.30)
SCHEMBL31114765 0.71 ALDH1A1 (0.38) ALDH1A1CES1CES2
SCHEMBL5622269 0.70 ALDH1A1 (0.35) ALDH1A1TDP1
SCHEMBL31114549 0.70 ALDH1A1 (0.37) ALDH1A1CES1CES2
SCHEMBL31114616 0.69 ALDH1A1 (0.35) ALDH1A1CES1CES2TDP1
SCHEMBL8854335 0.69 EPHX1 (0.39) ALDH1A1CES1CES2TDP1
SCHEMBL508215 0.68 LMNA (0.36) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116507668-B Additive stabilization 美国陶氏有机硅公司 2024-05-31 CN disclosed
CN-117377715-A Silicone composition and preparation thereof 美国陶氏有机硅公司 2024-01-09 CN disclosed
CN-114901725-B Polydiorganosiloxane preparation 美国陶氏有机硅公司 2023-09-08 CN disclosed
CN-116507668-A Additive stabilization 美国陶氏有机硅公司 2023-07-28 CN disclosed
CN-116209721-A Polydiorganosiloxane preparation 美国陶氏有机硅公司 2023-06-02 CN disclosed
CN-116171298-A Polydiorganosiloxane preparation 美国陶氏有机硅公司 2023-05-26 CN disclosed