SCHEMBL11329616

SCHEMBL11329616

CC[Si](CC)(N(C)C(C)=O)N(C)C(C)=O

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
CHRM1 P11229 2/20 0.31
CHRM2 P08172 1/20 0.31
CHRM4 P08173 1/20 0.31
CHRM5 P08912 1/20 0.31
CHRM3 P20309 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5622269 0.80 ALDH1A1 (0.35) ALDH1A1TDP1CHRM1CHRM2CHRM4
SCHEMBL29009685 0.79 ALDH1A1 (0.36) ALDH1A1TDP1
SCHEMBL31114683 0.76 ALDH1A1 (0.32) ALDH1A1TDP1CHRM1CHRM2CHRM4
SCHEMBL508215 0.72 LMNA (0.36) ALDH1A1CHRM1CHRM2CHRM4CHRM5
SCHEMBL452751 0.70 MEN1 (0.31)
SCHEMBL28790102 0.70 CHRM1 (0.32) ALDH1A1TDP1CHRM1CHRM2CHRM4
SCHEMBL31114550 0.69 ALDH1A1 (0.31) ALDH1A1TDP1
SCHEMBL537585 0.67
SCHEMBL449837 0.67 CHRM1 (0.35) ALDH1A1CHRM1CHRM2CHRM4CHRM5
SCHEMBL31114562 0.67 ALDH1A1 (0.30) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116507668-B Additive stabilization 美国陶氏有机硅公司 2024-05-31 CN disclosed
CN-117377715-A Silicone composition and preparation thereof 美国陶氏有机硅公司 2024-01-09 CN disclosed
CN-114901725-B Polydiorganosiloxane preparation 美国陶氏有机硅公司 2023-09-08 CN disclosed
CN-116507668-A Additive stabilization 美国陶氏有机硅公司 2023-07-28 CN disclosed
CN-116209721-A Polydiorganosiloxane preparation 美国陶氏有机硅公司 2023-06-02 CN disclosed
CN-116171298-A Polydiorganosiloxane preparation 美国陶氏有机硅公司 2023-05-26 CN disclosed
CN-114901725-A Preparation of polydiorganosiloxane 美国陶氏有机硅公司 2022-08-12 CN disclosed
CN-114787263-A Sealant composition 美国陶氏有机硅公司 2022-07-22 CN disclosed
US-4302571-A TERMINATED AT BOTH ENDS WITH SILANOIC HYDROXY GROUPS AND AN ORGANOSILANE OR ORGANOPOLYSILOXANE WITH HYDROLYZABLE GROUPS TO SERVE AS CROSSLINKING AGENTS SHIN-ETSU CHEMICAL CO., LTD. (JP) 1981-11-24 US disclosed