Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.44 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.44 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TSPO | P30536 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29009683 | 0.84 | TSHR (0.49) | TRPM8TSHRKMT2AMEN1NPC1 | |
| SCHEMBL29009654 | 0.83 | TP53 (0.49) | TSHRKMT2AMEN1NPC1RAB9A | |
| SCHEMBL22100824 | 0.81 | TRPM8 (0.72) | TRPM8TSHRKMT2AMEN1NPC1 | |
| SCHEMBL29009652 | 0.73 | TSHR (0.49) | TRPM8TSHRKMT2AMEN1NPC1 | |
| SCHEMBL7371332 | 0.72 | TRPM8 (0.63) | TRPM8TSHRKMT2AMEN1NPC1 | |
| SCHEMBL3064804 | 0.72 | TRPM8 (0.63) | TRPM8TSHRKMT2AMEN1NPC1 | |
| SCHEMBL8332050 | 0.72 | KMT2A (0.71) | TRPM8TSHRKMT2AMEN1NPC1 | |
| SCHEMBL22100763 | 0.70 | NPC1 (0.65) | TRPM8TSHRKMT2AMEN1NPC1 | |
| SCHEMBL2022652 | 0.70 | TSHR (0.43) | TRPM8TSHRKMT2AMEN1L3MBTL1 | |
| SCHEMBL3054619 | 0.69 | TRPM8 (0.52) | TRPM8TSHRKMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115010564-B | Preparation method of o-iodophenyl compound | 苏州大学 | 2024-03-19 | — | — | CN | disclosed |
| CN-115010564-A | Preparation method of o-iodophenyl compound | 苏州大学 | 2022-09-06 | — | — | CN | disclosed |