Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 4/20 | 0.46 |
| ▸ | BCHE | P06276 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | PTGES | O14684 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29009686 | 0.83 | TRPM8 (0.49) | NPC1RAB9ATSHRMEN1KMT2A | |
| SCHEMBL29009683 | 0.81 | TSHR (0.49) | NPC1RAB9AACHETSHRMEN1 | |
| SCHEMBL6778747 | 0.75 | NPC1 (0.55) | NPC1RAB9AACHETSHRMEN1 | |
| SCHEMBL6784816 | 0.75 | PTGES (0.60) | TP53NPC1RAB9AHTTSMN1; SMN2 | |
| SCHEMBL14174100 | 0.74 | NPC1 (0.63) | TP53NPC1RAB9ATSHRMEN1 | |
| SCHEMBL6779305 | 0.72 | PTGES (0.53) | TP53NPC1RAB9AHTTMEN1 | |
| SCHEMBL9865544 | 0.72 | TP53 (0.45) | TP53NPC1RAB9AHTTACHE | |
| SCHEMBL22100824 | 0.72 | TRPM8 (0.72) | NPC1RAB9AHTTTSHRMEN1 | |
| SCHEMBL6778659 | 0.72 | ALDH1A1 (0.49) | TP53HTTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL13503759 | 0.72 | NPC1 (0.57) | TP53NPC1RAB9ATSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115010564-B | Preparation method of o-iodophenyl compound | 苏州大学 | 2024-03-19 | — | — | CN | disclosed |
| CN-115010564-A | Preparation method of o-iodophenyl compound | 苏州大学 | 2022-09-06 | — | — | CN | disclosed |