Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | PTGES | O14684 | 3/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CFTR | P13569 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29009686 | 0.84 | TRPM8 (0.49) | TSHRKMT2ANPC1MEN1GAA | |
| SCHEMBL29009654 | 0.81 | TP53 (0.49) | TSHRPTGESALOX5KMT2ANPC1 | |
| SCHEMBL8332050 | 0.73 | KMT2A (0.71) | TSHRPTGESALOX5KMT2ANPC1 | |
| SCHEMBL22100824 | 0.73 | TRPM8 (0.72) | TSHRKMT2ANPC1MEN1GAA | |
| SCHEMBL6779305 | 0.69 | PTGES (0.53) | PTGESALOX5KMT2ANPC1MEN1 | |
| SCHEMBL29009652 | 0.69 | TSHR (0.49) | TSHRKMT2ANPC1MEN1GAA | |
| SCHEMBL3053571 | 0.69 | MAPK14 (0.63) | TSHRPTGESALOX5KMT2ANPC1 | |
| SCHEMBL3058316 | 0.69 | TSHR (0.49) | TSHRKMT2ANPC1MEN1GAA | |
| SCHEMBL1003508 | 0.69 | HDAC1 (0.71) | TSHRKMT2AMEN1CFTRL3MBTL1 | |
| SCHEMBL28778950 | 0.68 | CFTR (0.62) | TSHRKMT2AMEN1CFTRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115010564-B | Preparation method of o-iodophenyl compound | 苏州大学 | 2024-03-19 | — | — | CN | disclosed |
| CN-115010564-A | Preparation method of o-iodophenyl compound | 苏州大学 | 2022-09-06 | — | — | CN | disclosed |