Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 7/20 | 0.45 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 8/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 8/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | MMP12 | P39900 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | MMP14 | P50281 | 1/20 | 0.37 |
| ▸ | MMP16 | P51512 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.36 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.35 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30427701 | 1.00 | PTGS2 (0.45) | PTGS2CXCL8AKR1C3AKR1C2MMP1 | |
| SCHEMBL29010004 | 0.78 | AKR1C3 (0.44) | PTGS2CXCL8AKR1C3AKR1C2AKR1C4 | |
| SCHEMBL30428161 | 0.74 | AKR1C3 (0.52) | PTGS2CXCL8AKR1C3AKR1C2MMP1 | |
| SCHEMBL194437 | 0.74 | AKR1C3 (0.52) | PTGS2CXCL8AKR1C3AKR1C2MMP1 | |
| SCHEMBL14661316 | 0.72 | P2RX7 (0.61) | PTGS2CXCL8AKR1C3AKR1C2AKR1C4 | |
| SCHEMBL2204495 | 0.71 | PTGS2 (0.56) | PTGS2CXCL8AKR1C3AKR1C2MMP1 | |
| SCHEMBL25278886 | 0.71 | MMP2 (0.41) | PTGS2CXCL8MMP1MMP2MMP9 | |
| SCHEMBL8365340 | 0.71 | PTGS2 (0.43) | PTGS2CXCL8MMP1MMP2MMP9 | |
| SCHEMBL27928030 | 0.71 | AKR1C3 (0.50) | PTGS2AKR1C3AKR1C2PTGS1AKR1C4 | |
| SCHEMBL27928029 | 0.71 | AKR1C3 (0.50) | PTGS2AKR1C3AKR1C2PTGS1AKR1C4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116209433-A | Small molecule albumin binding agents | 俄勒冈健康科学大学 | 2023-06-02 | — | — | CN | disclosed |