SCHEMBL29010056

SCHEMBL29010056

CC(C(=O)O)c1cncc(C(F)(F)F)c1

nearest known ligand 0.47

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 12/20 0.47
AKR1C2 P52895 12/20 0.47
AGBL2 Q5U5Z8 1/20 0.43
PTGS2 P35354 2/20 0.40
KMT2A Q03164 1/20 0.40
TAS2R14 Q9NYV8 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.38
HDAC4 P56524 1/20 0.38
KDM4E B2RXH2 1/20 0.38
ALDH1A1 P00352 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3723398 0.82 AKR1C3 (0.56) AKR1C3AKR1C2PTGS2
SCHEMBL23972337 0.81 TAS2R14 (0.43) AGBL2TAS2R14SMN1; SMN2HDAC4KDM4E
SCHEMBL5373049 0.80 AKR1C3 (0.56) AKR1C3AKR1C2ALDH1A1
SCHEMBL1972547 0.80 AKR1C3 (0.56) AKR1C3AKR1C2ALDH1A1
SCHEMBL5766758 0.80 AKR1C3 (0.56) AKR1C3AKR1C2ALDH1A1
Hydrochloric Acid SCHEMBL30604428 0.80 TAS2R14 (0.43) AGBL2TAS2R14SMN1; SMN2HDAC4KDM4E
SCHEMBL15436228 0.80 ACACB (0.44) AGBL2KMT2ATAS2R14SMN1; SMN2HDAC4
SCHEMBL29947451 0.79 CYP11B1 (0.40) AGBL2KMT2ATAS2R14SMN1; SMN2KDM4E
SCHEMBL28827284 0.79 AKR1C3 (0.55) AKR1C3AKR1C2ALDH1A1
SCHEMBL26981280 0.79 CYP11B1 (0.40) AGBL2KMT2ATAS2R14SMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116209433-A Small molecule albumin binding agents 俄勒冈健康科学大学 2023-06-02 CN disclosed