Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.40 |
| ▸ | PDE2A | O00408 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PNMT | P11086 | 1/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | IDH1 | O75874 | 1/20 | 0.38 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP36 | Q9P275 | 1/20 | 0.35 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26981280 | 1.00 | CYP11B1 (0.40) | CYP11B1CYP11B2PDE2ASMN1; SMN2PNMT | |
| SCHEMBL19819840 | 0.84 | PNMT (0.41) | CYP11B1CYP11B2SMN1; SMN2PNMTGPR55 | |
| SCHEMBL10084726 | 0.84 | GPR55 (0.40) | CYP11B1CYP11B2SMN1; SMN2PNMTGPR55 | |
| SCHEMBL26743188 | 0.81 | GPR55 (0.38) | CYP11B1CYP11B2PDE2ASMN1; SMN2GPR55 | |
| SCHEMBL13018923 | 0.81 | GPR55 (0.38) | CYP11B1CYP11B2PDE2ASMN1; SMN2PNMT | |
| SCHEMBL30661349 | 0.81 | PDE2A (0.39) | CYP11B1CYP11B2PDE2ASMN1; SMN2PNMT | |
| SCHEMBL26743151 | 0.81 | PDE2A (0.39) | CYP11B1CYP11B2PDE2ASMN1; SMN2PNMT | |
| Hydrochloric Acid SCHEMBL28929728 | 0.79 | PDE2A (0.38) | CYP11B1CYP11B2PDE2ASMN1; SMN2PNMT | |
| Hydrochloric Acid SCHEMBL28929729 | 0.79 | PDE2A (0.38) | CYP11B1CYP11B2PDE2ASMN1; SMN2PNMT | |
| SCHEMBL29010056 | 0.79 | AKR1C3 (0.47) | SMN1; SMN2KDM4EALDH1A1AGBL2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122079983-A | FGFR3 inhibitor compounds | — | 2026-05-26 | — | — | CN | disclosed |
| CN-122079984-A | FGFR3 inhibitor compounds | — | 2026-05-26 | — | — | CN | disclosed |
| CN-122079985-A | FGFR3 inhibitor compounds | — | 2026-05-26 | — | — | CN | disclosed |
| CN-119421882-A | FGFR2 inhibitor compounds | 伊莱利利公司 | 2025-02-11 | — | — | CN | disclosed |
| EP-4301468-A1 | FGFR3 INHIBITOR COMPOUNDS | Eli Lilly and Company (US) | 2024-01-10 | — | — | EP | disclosed |
| WO-2022187443-A1 | FGFR3 INHIBITOR COMPOUNDS | ELI LILLY AND COMPANY (US) | 2022-09-09 | — | — | WO | disclosed |